Purification Media, BioSeparation Affinity, Protein A Beads Reagent – Agarose

The origin of Protein A is from the bacteria Staphylococcus aureus. Protein A is capable of binding most classes and subclasses of immunoglobulins from goat, rabbit, mouse and human.

Protein A beads are being routinely used for the isolation of IgG from several species of mammals. The binding of Protein A to IgGs vary between animal species and between IgG subclasses within the same species. Major limitation of protein A lies with the weak binding itpresents towards mouse IgG1, a common IgG subclass. Despite that, Protein A possesses usefulproperties that make it a popular choice for the isolation of most types of IgGs. Protein A binds IgGs through the Fc region of the molecules leaving the Fab region available for binding the antigen. Protein A Beads are commomnly used for antibodies purification and for the isolation of immune complexes by Immunoprecipitation.

Small volumes of Purification Media, BioSeparation Affinity, Protein A Beads reagent vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS635362 is a reagent targeting Purification Media, BioSeparation Affinity, Protein A Beads. Also known as Purification Media, BioSeparation Affinity, Protein A Beads (Agarose).