• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

WNT9B Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635545

Mouse Wnt-9b, previously called Wnt-14b or Wnt-15, is one of at least 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family of highly conserved, cysteine-rich secreted glycoproteins that are important for normal developmental processes… More details

$1280 / 0.025 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Wnt9b, Active Protein
Full Product Name
Wnt9b, Recombinant, Mouse (Wnt-14b, Wnt-15, Wingless-type MMTV (Mouse Mammary Tumor Virus) Integration Site Family Member)
Product Gene Name
WNT9B active protein
Form/Format
Supplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 0.1mm EDTA, 0.5% CHAPS, pH 6.8, 50ug BSA/1ug of cytokine. Reconstitute with 40-50% glycerol, PBS.
Purity/Purification
Purified
Purified
Preparation and Storage
4 degree C Do Not Freeze
Molecular Weight
Based on N-terminal aa sequencing, the recombinant mouse Wnt-9b starts at Ala 24 and has a calculated molecular mass of approximately 36.8kD. The recombinant mouse Wnt-9b migrates as an approximately 39-41kD protein in SDS-PAGE under reducing conditions.
Chromosome Location
Chromosome: 17; NC_000017.10 (44928952..44964096). Location: 17q21
OMIM
602864
3D Structure
ModBase 3D Structure for O14905
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Activity
Measured by its ability to induce alkaline phosphatase synthesis by C3H10T1/2 cells (,
The typical ED 50 range is 100-400ng/ml.

Storage and Stability:
12 months from date of receipt, 20 to 70 degree C as supplied.
1 month, 2 to 8 degree C under sterile conditions after reconstitution.
3 months, 20 to 70 degree C under sterile conditions after reconstitution.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Product Categories/Family for WNT9B active protein

Molecular Biology; MB-Wnt Proteins

Other Notes

Small volumes of WNT9B active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WNT9B purchase

MBS635545 is an active protein targeting WNT9B. Also known as Wnt9b, Recombinant, Mouse (Wnt-14b, Wnt-15, Wingless-type MMTV (Mouse Mammary Tumor Virus) Integration Site Family Member).

Additional Details

NCBI/Uniprot data below describe general gene information for WNT9B. It may not necessarily be applicable to this product.

NCBI GI #
37181546
NCBI GeneID
7484
NCBI Accession #
AAQ88584.1
UniProt Primary Accession #
O14905
UniProt Secondary Accession #
Q6UXT4; Q96Q09
UniProt Related Accession #
O14905
NCBI Official Full Name
WNT9B
NCBI Official Synonym Full Names
wingless-type MMTV integration site family, member 9B
NCBI Official Symbol
WNT9B
NCBI Official Synonym Symbols
WNT15; WNT14B
UniProt Protein Name
Protein Wnt-9b
UniProt Synonym Protein Names
Protein Wnt-14b; Protein Wnt-15
Protein Family
Protein
UniProt Gene Name
WNT9B
UniProt Synonym Gene Names
WNT14B; WNT15
UniProt Entry Name
WNT9B_HUMAN
NCBI Protein Information
protein Wnt-9b; protein Wnt-14b; wingless-type MMTV integration site family, member 15

NCBI Summary for WNT9B

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for WNT9B

WNT9B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Belongs to the Wnt family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region

Molecular Function: frizzled binding

Biological Process: positive regulation of catalytic activity; regulation of protein amino acid phosphorylation; Wnt receptor signaling pathway; cell fate commitment; response to retinoic acid; regulation of asymmetric cell division; Wnt receptor signaling pathway, planar cell polarity pathway; in utero embryonic development; multicellular organismal development; Wnt receptor signaling pathway through beta-catenin; palate development; embryonic cranial skeleton morphogenesis; cellular response to starvation; neuron differentiation; cell-cell signaling; ureteric bud branching; male genitalia development; regulation of tube size
Show more

Research Articles on WNT9B

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with WNT9B active protein

 Reference Product  PubMed Publications
 SFRP1 active protein  >4 publications with WNT9B and SFRP1
 FZD7 active protein  >3 publications with WNT9B and FZD7
 FZD6 active protein  >3 publications with WNT9B and FZD6
 FZD5 active protein  >2 publications with WNT9B and FZD5
 FZD2 active protein  >2 publications with WNT9B and FZD2
 FZD4 active protein  >2 publications with WNT9B and FZD4
 FZD8 active protein  >2 publications with WNT9B and FZD8
 FZD9 active protein  >1 publications with WNT9B and FZD9
 FZD10 active protein  >1 publications with WNT9B and FZD10

Pathways associated with WNT9B active protein

 Products by Pathway  Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram

Diseases associated with WNT9B active protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >7 publications with WNT9B and Neoplasms
 Kidney Diseases Antibodies  >5 publications with WNT9B and Kidney Diseases
 Breast Neoplasms Antibodies  >2 publications with WNT9B and Breast Neoplasms
 Weight Loss Antibodies  >2 publications with WNT9B and Weight Loss
 Heart Diseases Antibodies  >1 publications with WNT9B and Heart Diseases
 Nervous System Diseases Antibodies  >1 publications with WNT9B and Nervous System Diseases
 Body Weight Changes Antibodies  >1 publications with WNT9B and Body Weight Changes
 Inflammation Antibodies  >1 publications with WNT9B and Inflammation
 Neural Tube Defects Antibodies  >1 publications with WNT9B and Neural Tube Defects
 Death Antibodies  >1 publications with WNT9B and Death

Organs/Tissues associated with WNT9B active protein

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >22 publications with WNT9B and Kidney
 Muscle Antibodies  >4 publications with WNT9B and Muscle
 Brain Antibodies  >4 publications with WNT9B and Brain
 Eye Antibodies  >2 publications with WNT9B and Eye
 Testis Antibodies  >1 publications with WNT9B and Testis
 Ear Antibodies  >1 publications with WNT9B and Ear
 Ovary Antibodies  >1 publications with WNT9B and Ovary
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000