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Epidermal Growth Factor Receptor, L858R Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635591

The L858R mutation has been associated with non-small cell lung cancer patients who demonstrate clinical responsiveness to the tyrosine kinase inhibitor gefitinib (Iressa, ZD1839). More details

$1060 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Epidermal Growth Factor Receptor, L858R, Active Protein
Full Product Name
Epidermal Growth Factor Receptor, L858R, Recombinant, Human (erbB, EGFR)
Form/Format
Supplied as a liquid in 25mM Tris-HCl, pH 8.0, 138mM NaCl, 0.05% Tween-20, 50% glycerol, 3mM DTT.
Purity/Purification
Purified
0.7
Preparation and Storage
Aliquot to avoid repeated freezing and thawing and store at -70 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.
Molecular Weight
88kD
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Specific Activity
317pmol/min/ug
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Dilution: The enzyme reaction was carried out for 1h at room temperature in reaction buffer. Optimal dilutions to be determined by the researcher.

Other Notes

Small volumes of Epidermal Growth Factor Receptor, L858R active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Epidermal Growth Factor Receptor, L858R purchase

MBS635591 is an active protein targeting Epidermal Growth Factor Receptor, L858R. Also known as Epidermal Growth Factor Receptor, L858R, Recombinant, Human (erbB, EGFR).
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