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Monoamine Oxidase B (MAOB) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635685

Recombinant MAO-B comprises a 488 amino acid fragment (2-489) corresponding to the cytoplasmic domain fragment of the mature MAO-B protein and is expressed in E. coli with an amino-terminal hexahistidine tag.Monoamine oxidase B (MAO-B) is a flavin-containing… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Monoamine oxidase B (MAOB), Recombinant Protein
Full Product Name
Monoamine oxidase B, Recombinant, Human (MAO-B)
Product Gene Name
MAOB recombinant protein
Host
Human, Recombinant, E Coli
Form/Format
Supplied as a liquid in 1x Laemmli Buffer (25mM Tris-HCl pH6.8, 50mM DTT, 1% SDS, 0.1% bromophenol blue, 2.5% glycerol).
Purity/Purification
Purified
Purified
Preparation and Storage
For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
58,763 Da
Chromosome Location
Chromosome: X; NC_000023.10 (43625857..43741721, complement). Location: Xp11.23
OMIM
309860
3D Structure
ModBase 3D Structure for P27338

Product Categories/Family for MAOB recombinant protein

Molecular Biology; MB-Enzymes; Oxidase
Applications Tested/Suitable for MAOB recombinant protein
Western Blot (WB)
Application Notes for MAOB recombinant protein
Suitable for use in Western Blot., , Recommended Dilution:, Optimal dilutions to be determined by the researcher.

Other Notes

Small volumes of MAOB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAOB purchase

MBS635685 is a recombinant protein targeting MAOB. Also known as Monoamine oxidase B, Recombinant, Human (MAO-B). Host: Human, Recombinant, E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MAOB. It may not necessarily be applicable to this product.

NCBI GI #
398415
NCBI GeneID
4129
NCBI Accession #
AAB27229.1
UniProt Primary Accession #
P27338
UniProt Secondary Accession #
Q7Z6S2; B2R6R3; D3DWC3
UniProt Related Accession #
P27338
NCBI Official Full Name
monoamine oxidase B
NCBI Official Synonym Full Names
monoamine oxidase B
NCBI Official Symbol
MAOB
UniProt Protein Name
Amine oxidase [flavin-containing] B
UniProt Synonym Protein Names
Monoamine oxidase type B
Protein Family
Amine oxidase
UniProt Gene Name
MAOB
UniProt Synonym Gene Names
MAO-B
UniProt Entry Name
AOFB_HUMAN
NCBI Protein Information
amine oxidase [flavin-containing] B; amine oxidase [flavin-containing] B; MAO-B; MAO, brain; MAO, platelet; tyramine oxidase; adrenalin oxidase; monoamine oxidase type B

NCBI Summary for MAOB

The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008]
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UniProt Comments for MAOB

MAOB: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Belongs to the flavin monoamine oxidase family.

Protein type: Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - arginine and proline; EC 1.4.3.4; Oxidoreductase; Amino Acid Metabolism - tyrosine; Membrane protein, integral; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - histidine; Mitochondrial; Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - tryptophan

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: mitochondrial envelope; mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; integral to membrane

Molecular Function: amine oxidase activity; protein homodimerization activity; FAD binding; electron carrier activity

Biological Process: response to drug; dopamine catabolic process; response to toxin; response to lipopolysaccharide; negative regulation of serotonin secretion; positive regulation of dopamine metabolic process; response to selenium ion; substantia nigra development; response to ethanol; xenobiotic metabolic process; hydrogen peroxide biosynthetic process; response to aluminum ion; response to corticosterone stimulus
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Research Articles on MAOB

1. The rs1799836 SNP did not appear to correlated with attentional bias for facial expressions.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MAOB recombinant protein

 Reference Product  PubMed Publications
 COMT recombinant protein  >27 publications with MAOB and COMT
 CYP2D6 recombinant protein  >4 publications with MAOB and CYP2D6
 DBH recombinant protein  >3 publications with MAOB and DBH
 DDC recombinant protein  >3 publications with MAOB and DDC

Pathways associated with MAOB recombinant protein

 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alpha-synuclein Signaling Pathway antibodies  Alpha-synuclein Signaling Pathway Diagram
 Amine Oxidase Reactions Pathway antibodies  Amine Oxidase Reactions Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram

Diseases associated with MAOB recombinant protein

 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >60 publications with MAOB and Mental Disorders
 Brain Diseases Antibodies  >51 publications with MAOB and Brain Diseases
 Movement Disorders Antibodies  >41 publications with MAOB and Movement Disorders
 Parkinson Disease Antibodies  >34 publications with MAOB and Parkinson Disease
 Schizophrenia Antibodies  >13 publications with MAOB and Schizophrenia
 Depressive Disorder Antibodies  >5 publications with MAOB and Depressive Disorder
 Autistic Disorder Antibodies  >4 publications with MAOB and Autistic Disorder
 Seizures Antibodies  >3 publications with MAOB and Seizures
 Liver Diseases Antibodies  >2 publications with MAOB and Liver Diseases
 Learning Disorders Antibodies  >2 publications with MAOB and Learning Disorders

Organs/Tissues associated with MAOB recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >58 publications with MAOB and Brain
 Nerve Antibodies  >14 publications with MAOB and Nerve
 Liver Antibodies  >8 publications with MAOB and Liver
 Eye Antibodies  >6 publications with MAOB and Eye
 Muscle Antibodies  >5 publications with MAOB and Muscle
 Adrenal Gland Antibodies  >5 publications with MAOB and Adrenal Gland
 Kidney Antibodies  >4 publications with MAOB and Kidney
 Pituitary Gland Antibodies  >2 publications with MAOB and Pituitary Gland
 Thyroid Antibodies  >2 publications with MAOB and Thyroid
 Skin Antibodies  >2 publications with MAOB and Skin
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