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ADK, Aa22- 362 (adk) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635687

Adenosine kinase, also known as ADK is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine… More details

$790 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ADK, aa22- 362, Recombinant Protein
Full Product Name
ADK, aa22- 362, Recombinant, Human (Adenosine 5'-phosphotransferase, Adenosine Kinase, AK)
Product Gene Name
Host
E Coli
Form/Format
Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 20% glycerol, 1mM EDTA, 50mM sodium chloride.
Purity/Purification
Purified
~95% (SDS-PAGE)
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20 degree C. Aliquots are stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
40.5kD
Chromosome Location
NC_009725.1 (146608..147261)
3D Structure
ModBase 3D Structure for A7Z0Q9

SDS-Page of adk recombinant protein

15% SDS-PAGE using 3ug of A0882-62.
adk Recombinant Protein – Cat# MBS635687

Other Notes

Small volumes of adk recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for adk purchase

MBS635687 is a recombinant protein targeting adk. Also known as ADK, aa22- 362, Recombinant, Human (Adenosine 5'-phosphotransferase, Adenosine Kinase, AK). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for adk. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Adk
NCBI Official Symbol
adk
UniProt Protein Name
Adenylate kinase
UniProt Synonym Protein Names
ATP-AMP transphosphorylase; ATP:AMP phosphotransferase; Adenylate monophosphate kinase
UniProt Gene Name
adk
UniProt Synonym Gene Names
AK
UniProt Entry Name
KAD_BACA2
NCBI Protein Information
adenylate kinase

UniProt Comments for adk

Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism

By similarity. HAMAP-Rule MF_00235

Catalytic activity: ATP + AMP = 2 ADP. HAMAP-Rule MF_00235

Pathway: Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1. HAMAP-Rule MF_00235

Subunit structure: Monomer

By similarity. HAMAP-Rule MF_00235

Subcellular location: Cytoplasm

By similarity HAMAP-Rule MF_00235.

Domain: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain

By similarity. HAMAP-Rule MF_00235

Sequence similarities: Belongs to the adenylate kinase family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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