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Bcma:fc (BCMA) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635721

BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. Its downstream signaling is dependent on NF-kappaB and JNK. Binds human and mouse BAFF and APRIL. More details

$625 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BCMA:Fc, Active Protein
Full Product Name
BCMA:Fc, Recombinant, Human (B Cell Maturation Protein, CD269, TNFRSF17)
Sequence
The extracellu lar domain of human BCMA (aa 2-54) is fused at the C-terminus to the Fc portion of human IgG1.
Host
Human, HEK 293 cells
Form/Format
Supplied as a lyophilized powder in PBS pH 7.2. Reconstitute with 50ul ddH2O.
Purity/Purification
Highly Purified
>95% (SDS-PAGE)
Concentration
~1mg/ml (after reconstitution) (lot specific)
Specificity
Binds human and mouse BAFF and APRIL.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months after receipt at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
~40kD (SDS-PAGE)
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Blocks the binding of BAFF and APRIL to their receptors BCMA and TACI, inhibiting BAFF- and APRIL-mediated B cell activation.
Endotoxin
<0.01Eu/ig (LAL)

Product Categories/Family for BCMA:Fc active protein

Molecular Biology; MB-CD Markers

Other Notes

Small volumes of BCMA:Fc active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BCMA:Fc purchase

MBS635721 is an active protein targeting BCMA:Fc. Also known as BCMA:Fc, Recombinant, Human (B Cell Maturation Protein, CD269, TNFRSF17). Host: Human, HEK 293 cells.
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