• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Protein Tyrosine Phosphatase, Receptor Type, G (PTPRG) Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635794

Catalytic domain, (a.a. 801-1147), MW=39.6kD, expressed in an E. coli expression system. More details

$1065 / 0.02 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Protein Tyrosine Phosphatase, Receptor Type, G (PTPRG), Active Protein
Full Product Name
Protein Tyrosine Phosphatase, Receptor Type, G (801-1147), catalytic domain, Recombinant, Human (RPTPg)
Product Gene Name
Host
Recombinant, Human from E Coli
Species Reactivity
Human
Form/Format
25 mM Tris-HCl, pH 8.0, 75mM sodium chloride, 0.05% Tween-20, 50% glycerol, 2mM EDTA, 3mM DTT.
Purity/Purification
>95% by SDS-PAGE.
Preparation and Storage
-70 degree C
Stability: 6 months at -20 degree C
Molecular Weight
162,003 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (61547243..62280573). Location: 3p21-p14
OMIM
176886
3D Structure
ModBase 3D Structure for P23470
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Specific Activity
10 U/ug. One unit will hydrolyze 1 nmol p-nitrophenyl phosphate per minute at pH 7.4 and 30 degree C
Assay Buffer
50 mM HEPES, pH 7.4, 2 mM EDTA, 3 mM DTT, 100 mM NaCl, 50mM pNPP.
Location
3p21-p14
Application Notes for PTPRG active protein
useful for the study of enzyme kinetics, regulation, and to dephosphorylate target substrates.

Other Notes

Small volumes of PTPRG active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTPRG purchase

MBS635794 is an active protein targeting PTPRG. Also known as Protein Tyrosine Phosphatase, Receptor Type, G (801-1147), catalytic domain, Recombinant, Human (RPTPg). Reactive in Human. Host: Recombinant, Human from E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPRG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Protein tyrosine phosphatase, receptor type, G
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type, G
NCBI Official Symbol
PTPRG
NCBI Official Synonym Symbols
PTPG; HPTPG; RPTPG; R-PTP-GAMMA
UniProt Protein Name
Receptor-type tyrosine-protein phosphatase gamma
UniProt Gene Name
PTPRG
UniProt Synonym Gene Names
PTPG; Protein-tyrosine phosphatase gamma; R-PTP-gamma
UniProt Entry Name
PTPRG_HUMAN
NCBI Protein Information
receptor-type tyrosine-protein phosphatase gamma; H_RG317H01.1; protein tyrosine phosphatase gamma; protein-tyrosine phosphatase gamma; receptor tyrosine phosphatase gamma; receptor-type protein phosphatase gamma; receptor type protein tyrosine phosphatase gamma; protein tyrosine phosphatase, receptor type, gamma polypeptide

NCBI Summary for PTPRG

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for PTPRG

PTPRG: Possesses tyrosine phosphatase activity. Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; EC 3.1.3.48; Receptor protein phosphatase, tyrosine; Phosphatase

Chromosomal Location of Human Ortholog: 3p21-p14

Cellular Component: extracellular space; integral to plasma membrane

Molecular Function: identical protein binding; protein binding; transmembrane receptor protein tyrosine phosphatase activity; protein tyrosine phosphatase activity

Biological Process: brain development; transmembrane receptor protein tyrosine kinase signaling pathway
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PTPRG active protein

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000