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Jagged-1:fc Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635848

Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast… More details

$530 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Jagged-1:Fc, Active Protein
Full Product Name
Jagged-1:Fc, Recombinant, Human (Protein Jagged-1, hJ1, CD339, JAG1)
Sequence
Signal peptide and extracellu lar domain of human Jagged-1 (HJ1; CD339) (aa 1-1067) are fused at the C-terminus to the Fc portion of human IgG1.
Host
Human, HEK 293 cells
Form/Format
Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.
Purity/Purification
Highly Purified
>90% (SDS-PAGE)
Preparation and Storage
Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Working aliquots are stable for up to 3 months when stored at -20 degree C.
Molecular Weight
~150kD (SDS-PAGE)
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Inhibits adipogenesis of mesenchymal stem cells (MSCs). Induces Hes-1 in 3T3L-1 cells.

Product Categories/Family for Jagged-1:Fc active protein

Molecular Biology; MB-Notch Proteins

Other Notes

Small volumes of Jagged-1:Fc active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Jagged-1:Fc purchase

MBS635848 is an active protein targeting Jagged-1:Fc. Also known as Jagged-1:Fc, Recombinant, Human (Protein Jagged-1, hJ1, CD339, JAG1). Host: Human, HEK 293 cells.
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