KRT14 Recombinant Protein – Cat# MBS635879

Cytokeratin 14 (KRT14) Recombinant Protein

Name: KRT14 Recombinant Protein; Cytokeratin 14; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS635879
Price: 750 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635879

Keratins are a class of fibrous proteins or scleroproteins important both as structural proteins and as keys to the study of protein conformation. The family represents the principal constituent of epidermis, hair, nails, horny tissues, and the organic matrix… More details

$750 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cytokeratin 14 (KRT14), Recombinant Protein

Full Product Name

Cytokeratin 14, Recombinant, Human

Product Gene Name

KRT14 recombinant protein

Host

E Coli

Form/Format

Supplied as a lyophilized powder in 30mM Tris-HCl, pH 8.0, 9.5M urea, 2mM EDTA, 10mM methylammonium chloride. Reconstitute with sterile ddH2O to a concentration >100ug/ml, which can then be further diluted to other aqueous solutions. 0.1% BSA or HSA is re

Purity/Purification

Highly Purified
95% by RP-HPLC or SDS-PAGE. Chromatographically purified.

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

~51kD

OMIM

125595

3D Structure

ModBase 3D Structure for P02533

Note

0.1% BSA or HSA is recommended for long term storage.

Product Categories/Family for KRT14 recombinant protein

Molecular Biology; MB-Keratin; Cytokeratin

Other Notes

Small volumes of KRT14 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KRT14 purchase

MBS635879 is a recombinant protein targeting KRT14. Also known as Cytokeratin 14, Recombinant, Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT14. It may not necessarily be applicable to this product.

NCBI GI #

355568680

NCBI Accession #

EHH24961.1

UniProt Primary Accession #

P02533

UniProt Secondary Accession #

Q14715; Q53XY3; Q9BUE3; Q9UBN2; Q9UBN3; Q9UCY4

NCBI Official Full Name

Cytokeratin-14

UniProt Protein Name

Keratin, type I cytoskeletal 14

UniProt Synonym Protein Names

Cytokeratin-14; CK-14; Keratin-14

Protein Family

Keratin

UniProt Gene Name

KRT14

UniProt Synonym Gene Names

CK-14; K14

UniProt Entry Name

K1C14_HUMAN

UniProt Comments for KRT14

K14: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K5.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: cytoplasm; keratin filament; intermediate filament; nucleus; cytosol

Molecular Function: protein binding; structural constituent of cytoskeleton

Biological Process: epidermis development; hemidesmosome assembly; epithelial cell differentiation; response to zinc ion; response to ionizing radiation; intermediate filament bundle assembly; aging; hair cycle

Disease: Epidermolysis Bullosa Simplex, Localized; Epidermolysis Bullosa Simplex, Generalized; Dermatopathia Pigmentosa Reticularis; Epidermolysis Bullosa Simplex, Autosomal Recessive 1; Naegeli Syndrome; Epidermolysis Bullosa Simplex, Dowling-meara Type

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with KRT14 recombinant protein

Reference Product	PubMed Publications
KRT5 recombinant protein	>73 publications with KRT14 and KRT5
EGFR recombinant protein	>7 publications with KRT14 and EGFR
DST recombinant protein	>2 publications with KRT14 and DST
IVL recombinant protein	>1 publications with KRT14 and IVL
CREBBP recombinant protein	>1 publications with KRT14 and CREBBP

Diseases associated with KRT14 recombinant protein

Disease Name	Pubmed Publications
Epidermolysis Bullosa Simplex Antibodies	>88 publications with KRT14 and Epidermolysis Bullosa Simplex
Neoplasms Antibodies	>80 publications with KRT14 and Neoplasms
Carcinoma Antibodies	>56 publications with KRT14 and Carcinoma
Carcinoma, Squamous Cell Antibodies	>36 publications with KRT14 and Carcinoma, Squamous Cell
Disease Models, Animal Antibodies	>21 publications with KRT14 and Disease Models, Animal
Hyperplasia Antibodies	>19 publications with KRT14 and Hyperplasia
Skin Neoplasms Antibodies	>18 publications with KRT14 and Skin Neoplasms
Breast Neoplasms Antibodies	>17 publications with KRT14 and Breast Neoplasms
Necrosis Antibodies	>13 publications with KRT14 and Necrosis
Cell Transformation, Neoplastic Antibodies	>13 publications with KRT14 and Cell Transformation, Neoplastic

Organs/Tissues associated with KRT14 recombinant protein

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>145 publications with KRT14 and Skin
Blood Antibodies	>23 publications with KRT14 and Blood
Mouth Antibodies	>15 publications with KRT14 and Mouth
Lung Antibodies	>8 publications with KRT14 and Lung
Esophagus Antibodies	>8 publications with KRT14 and Esophagus
Mammary Gland Antibodies	>7 publications with KRT14 and Mammary Gland
Eye Antibodies	>6 publications with KRT14 and Eye
Connective Tissue Antibodies	>6 publications with KRT14 and Connective Tissue
Liver Antibodies	>6 publications with KRT14 and Liver
Cervix Antibodies	>5 publications with KRT14 and Cervix