UBE2D1 Recombinant Protein – Cat# MBS635903

Ubiquitin-Conjugating Enzyme E2 D1, His-Tag (UBE2D1) Recombinant Protein

Name: UBE2D1 Recombinant Protein; MyBioSource
Brand: MyBioSource
SKU: MBS635903
Price: 700 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635903

UbcH5a is highly homologous to the S. cerevisiae Ubc4/5 family of E2 enzymes demonstrated to be essential for degradation of regulatory and abnormal proteins. UbcH5a, together with UbcH5b and UbcH5c, are the most active class of E2 enzymes in cell extracts… More details

$700 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ubiquitin-conjugating Enzyme E2 D1, His-tag (Ube2d1), Recombinant Protein

Full Product Name

Ubiquitin-conjugating Enzyme E2 D1, Recombinant, Human, His-tag (UBE2D1, Stimulator of Fe Transport, SFT, UBC4/5 Homolog, UBC5A, UbcH5, UBCH5A, Ubiquitin Carrier Protein D1, Ubiquitin-conjugating Enzyme E2(17)KB 1, Ubiquitin-conjugating Enzyme E2-17kD 1

Product Gene Name

Ube2d1 recombinant protein

Product Synonym Names

Form/Format

Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 0.5mM DTT.

Purity/Purification

Highly Purified
~95% (SDS-PAGE)

Preparation and Storage

Aliquot to avoid repeated freezing and thawing and store at -70 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

~17kD

Chromosome Location

Chromosome: 10; NC_000076.6 (71254980..71285262, complement). Location: 10 B5.3; 10

3D Structure

ModBase 3D Structure for P61080

Product Categories/Family for Ube2d1 recombinant protein

Molecular Biology; MB-Ubiquitin Ligases

Other Notes

Small volumes of Ube2d1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ube2d1 purchase

MBS635903 is a recombinant protein targeting Ube2d1. Also known as Ubiquitin-conjugating Enzyme E2 D1, Recombinant, Human, His-tag (UBE2D1, Stimulator of Fe Transport, SFT, UBC4/5 Homolog, UBC5A, UbcH5, UBCH5A, Ubiquitin Carrier Protein D1, Ubiquitin-conjugating Enzyme E2(17)KB 1, Ubiquitin-conjugating Enzyme E2-17kD 1.

Additional Details

NCBI/Uniprot data below describe general gene information for Ube2d1. It may not necessarily be applicable to this product.

NCBI GI #

21703838

NCBI GeneID

216080

NCBI Accession #

NP_663395.1

UniProt Primary Accession #

P61080

UniProt Related Accession #

P61080

GenBank Nucleotide #

NM_145420.2

NCBI Official Full Name

ubiquitin-conjugating enzyme E2 D1

NCBI Official Synonym Full Names

ubiquitin-conjugating enzyme E2D 1

NCBI Official Symbol

Ube2d1

NCBI Official Synonym Symbols

UBCH5

UniProt Protein Name

Ubiquitin-conjugating enzyme E2 D1

UniProt Synonym Protein Names

Ubiquitin carrier protein D1; Ubiquitin-conjugating enzyme E2(17)KB 1; Ubiquitin-conjugating enzyme E2-17 kDa 1; Ubiquitin-protein ligase D1

Protein Family

Ubiquitin-conjugating enzyme

UniProt Gene Name

Ube2d1

UniProt Entry Name

UB2D1_MOUSE

NCBI Protein Information

ubiquitin-conjugating enzyme E2 D1; E2(17)KB 1; ubiquitin-protein ligase D1; ubiquitin carrier protein D1; ubiquitin-conjugating enzyme E2(17)KB 1; ubiquitin-conjugating enzyme E2-17 kDa 1; ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog

UniProt Comments for Ube2d1

UBE2D1: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4. Belongs to the ubiquitin-conjugating enzyme family.

Protein type: Ubiquitin conjugating system; Ubiquitin ligase; Ligase; EC 6.3.2.19

Cellular Component: protein complex; cytoplasm; ubiquitin ligase complex

Molecular Function: protein binding; nucleotide binding; ubiquitin-protein ligase activity; ATP binding; ligase activity

Biological Process: ubiquitin-dependent protein catabolic process; protein polyubiquitination; positive regulation of protein ubiquitination

Research Articles on Ube2d1

1. significantly elevated levels of SFT/UbcH5A mRNA in the neonatal mouse and its localization to choroid plexus suggest that this factor may contribute to the rapid rate of brain iron uptake that occurs in the early postnatal period

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Ube2d1 recombinant protein

Reference Product	PubMed Publications
Cul2 recombinant protein	>1 publications with Ube2d1 and Cul2

Pathways associated with Ube2d1 recombinant protein

Products by Pathway	Pathway Diagram
APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies	APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
APC/C:Cdc20 Mediated Degradation Of Cyclin B Pathway antibodies	APC/C:Cdc20 Mediated Degradation Of Cyclin B Pathway Diagram
APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies	APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies	APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies	APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
Activated TLR4 Signalling Pathway antibodies	Activated TLR4 Signalling Pathway Diagram
Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies	Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
Autodegradation Of Cdh1 By Cdh1:APC/C Pathway antibodies	Autodegradation Of Cdh1 By Cdh1:APC/C Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle Checkpoints Pathway antibodies	Cell Cycle Checkpoints Pathway Diagram

Diseases associated with Ube2d1 recombinant protein

Disease Name	Pubmed Publications
Anemia Antibodies	>3 publications with Ube2d1 and Anemia
Fibrosis Antibodies	>2 publications with Ube2d1 and Fibrosis
Neoplasms Antibodies	>2 publications with Ube2d1 and Neoplasms
Eye Diseases Antibodies	>1 publications with Ube2d1 and Eye Diseases
Anoxia Antibodies	>1 publications with Ube2d1 and Anoxia
Liver Neoplasms Antibodies	>1 publications with Ube2d1 and Liver Neoplasms
Nervous System Diseases Antibodies	>1 publications with Ube2d1 and Nervous System Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with Ube2d1 and Carcinoma, Hepatocellular
Inflammation Antibodies	>1 publications with Ube2d1 and Inflammation
Necrosis Antibodies	>1 publications with Ube2d1 and Necrosis

Organs/Tissues associated with Ube2d1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>7 publications with Ube2d1 and Intestine
Kidney Antibodies	>3 publications with Ube2d1 and Kidney
Brain Antibodies	>3 publications with Ube2d1 and Brain
Lung Antibodies	>2 publications with Ube2d1 and Lung
Embryonic Tissue Antibodies	>2 publications with Ube2d1 and Embryonic Tissue
Heart Antibodies	>1 publications with Ube2d1 and Heart
Muscle Antibodies	>1 publications with Ube2d1 and Muscle
Bone Antibodies	>1 publications with Ube2d1 and Bone
Eye Antibodies	>1 publications with Ube2d1 and Eye
Thymus Antibodies	>1 publications with Ube2d1 and Thymus