Galectin-3 Binding Protein (LGALS3) Active Protein

Name: LGALS3 Active Protein; MyBioSource
Brand: MyBioSource
SKU: MBS635971
Price: 1215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635971

Galectin-3 binding protein (Galectin-3BP), called CyCAP (cyclophilin C-associated protein) in the mouse, is a secreted glycoprotein of the scavenger receptor cysteine-rich (SRCR) super family. Mouse Galectin-3BP is generally considered the paralog of human… More details

$1215 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Galectin-3 Binding Protein (LGALS3), Active Protein

Full Product Name

Galectin-3 Binding Protein, Recombinant, Mouse (MAC-2BP)

Product Gene Name

LGALS3 active protein

Form/Format

Supplied as a lyophilized powder from 20mM MOPS, 100mM sodium chloride, 10mM Imidazole, 5% trehalose. Reconstitute with 167ul sterile PBS

Purity/Purification

>90% by SDS-PAGE under reducing conditions and visualized by silver stain.

Preparation and Storage

Lyophilized powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

63.3kD

Chromosome Location

Chromosome: 8; NC_006590.3 (30977374..30994712). Location: chromosome: 8

3D Structure

ModBase 3D Structure for P38486

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Measured by its binding ability in a functional ELISA. When rmMAC-2BP is coated at 1ug/ml (100ul/well), rhGalectin-3 binds with an apparent KD <5nM.

Endotoxin Level

<0.1EU/ug (LAL)

Source

Recombinant protein corresponding to Thr19-Val577 with a C-terminal 6-His tag from mouse Galectin-3 Binding Protein, expressed in NS0 cells. (NP_035280)

SDS-PAGE

80-90kD, reducing conditions.

Product Categories/Family for LGALS3 active protein

Molecular Biology; MB-Binding Proteins

Other Notes

Small volumes of LGALS3 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LGALS3 purchase

MBS635971 is an active protein targeting LGALS3. Also known as Galectin-3 Binding Protein, Recombinant, Mouse (MAC-2BP).

Additional Details

NCBI/Uniprot data below describe general gene information for LGALS3. It may not necessarily be applicable to this product.

NCBI GI #

308081799

NCBI GeneID

404021

NCBI Accession #

NP_001183972.1

UniProt Primary Accession #

P38486

UniProt Related Accession #

P38486

GenBank Nucleotide #

NM_001197043.1

NCBI Official Full Name

galectin-3

NCBI Official Symbol

LGALS3

NCBI Official Synonym Symbols

Gal-3; CBP 35; Galectin-3

UniProt Protein Name

Galectin-3

UniProt Synonym Protein Names

35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; IgE-binding protein; Laminin-binding protein; Lectin L-29; Mac-2 antigen

Protein Family

Galectin-3-binding protein

UniProt Gene Name

LGALS3

UniProt Synonym Gene Names

Gal-3; CBP 35

UniProt Entry Name

LEG3_CANFA

NCBI Protein Information

galectin-3; lectin L-29; 35 kDa lectin; mac-2 antigen; igE-binding protein; laminin-binding protein; galactose-specific lectin 3; carbohydrate-binding protein 35; beta-galactosides-binding lectin; lectin, galactoside-binding, soluble, 3 (galectin 3)

UniProt Comments for LGALS3

Galectin-3: galactose-specific lectin which binds IgE. Expressed at a high level in the colonic epithelium. Also abundant in activated macrophages.

Protein type: Motility/polarity/chemotaxis; Cell surface; Extracellular matrix

Cellular Component: spliceosome; cytoplasm; extracellular region

Molecular Function: IgE binding; carbohydrate binding

Biological Process: RNA splicing; innate immune response; mRNA processing; cell differentiation

Research Articles on LGALS3

1. Galectin-3 staining was positive in 11 of 15 (73%) carcinomas, 5 of 19 (26%) adenomas, 1 of 8 (12%) hyperplasias, and 0 of 6 normal tissues.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LGALS3 active protein

Reference Product	PubMed Publications
LGALS3BP active protein	>34 publications with LGALS3 and LGALS3BP
GEMIN4 active protein	>5 publications with LGALS3 and GEMIN4
SUFU active protein	>1 publications with LGALS3 and SUFU

Pathways associated with LGALS3 active protein

Products by Pathway	Pathway Diagram
Advanced Glycosylation Endproduct Receptor Signaling Pathway antibodies	Advanced Glycosylation Endproduct Receptor Signaling Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Organs/Tissues associated with LGALS3 active protein

Organ/Tissue Name	Pubmed Publications
Thyroid Antibodies	>272 publications with LGALS3 and Thyroid
Brain Antibodies	>120 publications with LGALS3 and Brain
Kidney Antibodies	>98 publications with LGALS3 and Kidney
Eye Antibodies	>41 publications with LGALS3 and Eye
Connective Tissue Antibodies	>35 publications with LGALS3 and Connective Tissue
Artery Antibodies	>30 publications with LGALS3 and Artery