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UCK1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6361076

Uridine/cytidine kinase-1 (EC 2.7.1.48) is a pyrimidine ribonucleoside kinase that catalyzes the phosphorylation of uridine and cytidine to form uridine monophosphate (UMP) and cytidine monophosphate (CMP) (Van Rompay et al., 2001 [PubMed 11306702]). More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
UCK1, Polyclonal Antibody
Full Product Name
UCK1, CT (UCK1, URK1, Uridine-cytidine kinase 1, Cytidine monophosphokinase 1, Uridine monophosphokinase 1) (MaxLight 550)
Product Gene Name
Product Synonym Names
UCK1; URK1; Uridine-cytidine kinase 1; Cytidine monophosphokinase 1; Uridine monophosphokinase 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
17.5 kDa (152aa)
OMIM
AF237290 mRNA
3D Structure
ModBase 3D Structure for Q9HA47
Immunogen
UCK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human UCK1.
Conjugate
MaxLight550
Note
Preservative Free

Product Categories/Family for anti-UCK1 antibody

Applications Tested/Suitable for anti-UCK1 antibody
Western Blot (WB), FLISA
Application Notes for anti-UCK1 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-UCK1 antibody

Virovic Jukic, L., et al. J. Biomed. Sci. 15(2):205-213(2008). Humphray, S.J., et al. Nature 429(6990):369-374(2004). Van Rompay, A.R., et al. Mol. Pharmacol. 59(5):1181-1186(2001).

Other Notes

Small volumes of anti-UCK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UCK1 purchase

MBS6361076 is an antibody targeting UCK1. Also known as UCK1, CT (UCK1, URK1, Uridine-cytidine kinase 1, Cytidine monophosphokinase 1, Uridine monophosphokinase 1) (MaxLight 550). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for UCK1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
uridine-cytidine kinase 1 isoform a
NCBI Official Synonym Full Names
uridine-cytidine kinase 1
NCBI Official Symbol
UCK1
NCBI Official Synonym Symbols
URK1
UniProt Protein Name
Uridine-cytidine kinase 1
UniProt Synonym Protein Names
Cytidine monophosphokinase 1; Uridine monophosphokinase 1
UniProt Gene Name
UCK1
UniProt Synonym Gene Names
URK1; UCK 1
NCBI Protein Information
uridine-cytidine kinase 1

NCBI Summary for UCK1

This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. [provided by RefSeq, May 2012]
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UniProt Comments for UCK1

Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N4-acetylcytidine, N4-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N4-anisoylcytidine.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UCK1 antibody

 Reference Product  PubMed Publications
 DCK antibody  >2 publications with UCK1 and DCK

Diseases associated with anti-UCK1 antibody

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