C1QTNF5 Recombinant Protein – Cat# MBS636155

CTRP5 (C1QTNF5) Recombinant Protein

Name: C1QTNF5 Recombinant Protein; CTRP5; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS636155
Price: 525 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS636155

CTRP5 (C1qTNF-related protein 5; C1QTNF5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels… More details

$525 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CTRP5 (C1QTNF5), Recombinant Protein

Full Product Name

CTRP5, Recombinant, Human (His) (Complement C1q Tumor Necrosis Factor-related Protein 5, C1QTNF5)

Product Gene Name

C1QTNF5 recombinant protein

Sequence

Human CTRP5 (aa 16-243) is fused at the N-terminus to a His-tag.

Host

Human, E Coli

Form/Format

Supplied as a lyophilized powder from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl. Recontitute with sterile dH2O

Purity/Purification

>90%

Preparation and Storage

Lyopholized powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute, aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 3 months. For maximum recovery of product centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

~26kD (SDS-PAGE)

Chromosome Location

Chromosome: 11; NC_000011.9 (119209644..119217383, complement). Location: 11q23.3

OMIM

605670

3D Structure

ModBase 3D Structure for Q9BXJ0

Endotoxin

<1EU/ug

Product Categories/Family for C1QTNF5 recombinant protein

Growth Factors; Cytokines; Growth Factors-TNF

Other Notes

Small volumes of C1QTNF5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C1QTNF5 purchase

MBS636155 is a recombinant protein targeting C1QTNF5. Also known as CTRP5, Recombinant, Human (His) (Complement C1q Tumor Necrosis Factor-related Protein 5, C1QTNF5). Host: Human, E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for C1QTNF5. It may not necessarily be applicable to this product.

NCBI GI #

510025462

NCBI GeneID

114902

NCBI Accession #

NP_001265360.1

UniProt Primary Accession #

Q9BXJ0

UniProt Secondary Accession #

Q335M2; Q8N6P2; Q9UFX4; A6NDD3; B0YJ35

UniProt Related Accession #

Q9BXJ0

GenBank Nucleotide #

NM_001278431.1

NCBI Official Full Name

complement C1q tumor necrosis factor-related protein 5

NCBI Official Synonym Full Names

C1q and tumor necrosis factor related protein 5

NCBI Official Symbol

C1QTNF5

NCBI Official Synonym Symbols

CTRP5

UniProt Protein Name

Complement C1q tumor necrosis factor-related protein 5

Protein Family

Complement C1q tumor necrosis factor-related protein

UniProt Gene Name

C1QTNF5

UniProt Synonym Gene Names

CTRP5

UniProt Entry Name

C1QT5_HUMAN

NCBI Protein Information

complement C1q tumor necrosis factor-related protein 5; myonectin; C1q TNF-alpha-related protein 5

NCBI Summary for C1QTNF5

This gene encodes a member of a family of proteins that function as components of basement membranes and may play a role in cell adhesion. Mutations in this gene have been associated with late-onset retinal degeneration. The protein may be encoded by either a bicistronic transcript including sequence from the upstream membrane frizzled-related protein gene (MFRP), or by a monocistronic transcript expressed from an internal promoter. [provided by RefSeq, Jun 2013]

UniProt Comments for C1QTNF5

C1QTNF5: Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD). LORD is an autosomal dominant disorder characterized by onset in the fifth to sixth decade with night blindness and punctate yellow-white deposits in the retinal fundus, progressing to severe central and peripheral degeneration, with choroidal neovascularization and chorioretinal atrophy.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: collagen

Disease: Late-onset Retinal Degeneration

Research Articles on C1QTNF5

1. C1QTNF5 retinopathy is an autosomal dominant LORD resulting in a complex ocular phenotype involving the RPE and ciliary epithelium. SD-OCT findings revealed widespread photoreceptor loss and diffuse choroidal thinning.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with C1QTNF5 recombinant protein

Reference Product	PubMed Publications
MFRP recombinant protein	>6 publications with C1QTNF5 and MFRP
TIMP3 recombinant protein	>1 publications with C1QTNF5 and TIMP3

Diseases associated with C1QTNF5 recombinant protein

Disease Name	Pubmed Publications
Macular Degeneration Antibodies	>11 publications with C1QTNF5 and Macular Degeneration
Necrosis Antibodies	>9 publications with C1QTNF5 and Necrosis
Late-Onset Retinal Degeneration Antibodies	>8 publications with C1QTNF5 and Late-Onset Retinal Degeneration
Disease Models, Animal Antibodies	>7 publications with C1QTNF5 and Disease Models, Animal
Atrophy Antibodies	>5 publications with C1QTNF5 and Atrophy
Lens Diseases Antibodies	>4 publications with C1QTNF5 and Lens Diseases
Eye Abnormalities Antibodies	>3 publications with C1QTNF5 and Eye Abnormalities
Inflammation Antibodies	>2 publications with C1QTNF5 and Inflammation
Weight Loss Antibodies	>1 publications with C1QTNF5 and Weight Loss
Kidney Diseases Antibodies	>1 publications with C1QTNF5 and Kidney Diseases

Organs/Tissues associated with C1QTNF5 recombinant protein

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>20 publications with C1QTNF5 and Eye
Connective Tissue Antibodies	>1 publications with C1QTNF5 and Connective Tissue
Skin Antibodies	>1 publications with C1QTNF5 and Skin
Vascular Antibodies	>1 publications with C1QTNF5 and Vascular
Muscle Antibodies	>1 publications with C1QTNF5 and Muscle
Ovary Antibodies	>1 publications with C1QTNF5 and Ovary
Placenta Antibodies	>1 publications with C1QTNF5 and Placenta
Brain Antibodies	>1 publications with C1QTNF5 and Brain