STK10 Recombinant Protein

Name: STK10 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS636167
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS636167

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in… More details

$1060 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

STK10, Recombinant Protein

Full Product Name

STK10, Recombinant, Human (Serine/threonine Kinase 10, LOK, Lymphocyte-oriented Kinase, PRO2729, Serine/threonine-protein Kinase 10)

Product Gene Name

STK10 recombinant protein

Host

Recombinant human STK10, aa1-

Purity/Purification

Purified
>=60%

Preparation and Storage

-70 degree C

Molecular Weight

43.2kD.

Chromosome Location

Chromosome: 5; NC_000005.9 (171469074..171615346, complement). Location: 5q35.1

OMIM

273300

3D Structure

ModBase 3D Structure for O94804

Product Categories/Family for STK10 recombinant protein

Molecular Biology; MB-Protein Kinases

Other Notes

Small volumes of STK10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STK10 purchase

MBS636167 is a recombinant protein targeting STK10. Also known as STK10, Recombinant, Human (Serine/threonine Kinase 10, LOK, Lymphocyte-oriented Kinase, PRO2729, Serine/threonine-protein Kinase 10). Host: Recombinant human STK10, aa1-.

Additional Details

NCBI/Uniprot data below describe general gene information for STK10. It may not necessarily be applicable to this product.

NCBI GI #

126362971

NCBI GeneID

6793

NCBI Accession #

NP_005981.3

UniProt Primary Accession #

O94804

UniProt Secondary Accession #

Q6NSK0; Q9UIW4; A6ND35; B2R8F5; B3KMY1

UniProt Related Accession #

O94804

GenBank Nucleotide #

NM_005990.3

NCBI Official Full Name

serine/threonine-protein kinase 10

NCBI Official Synonym Full Names

serine/threonine kinase 10

NCBI Official Symbol

STK10

NCBI Official Synonym Symbols

LOK; PRO2729

UniProt Protein Name

Serine/threonine-protein kinase 10

UniProt Synonym Protein Names

Lymphocyte-oriented kinase

Protein Family

Serine/threonine-protein kinase

UniProt Gene Name

STK10

UniProt Synonym Gene Names

LOK

UniProt Entry Name

STK10_HUMAN

NCBI Protein Information

serine/threonine-protein kinase 10; lymphocyte-oriented kinase

NCBI Summary for STK10

This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008]

UniProt Comments for STK10

LOK: a protein kinase of the STE20 family. Highly expressed in hematopoietic tissue. May cooperate with SLK to regulate Plk1 function in human cells.

Protein type: Kinase, protein; Protein kinase, STE; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; SLK subfamily

Chromosomal Location of Human Ortholog: 5q35.1

Cellular Component: cytoplasm; plasma membrane

Molecular Function: identical protein binding; protein serine/threonine kinase activity; protein binding; polo kinase kinase activity; protein homodimerization activity; ATP binding

Biological Process: protein amino acid autophosphorylation; cell cycle; protein amino acid phosphorylation

Research Articles on STK10

1. It was shown that lymphocyte-oriented and STE20 kinase were sufficient to restrict ezrin function to the apical domain. Both kinases were enriched in microvilli and locally activated there.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with STK10 recombinant protein

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>1 publications with STK10 and Disease Models, Animal
Inflammation Antibodies	>1 publications with STK10 and Inflammation

Organs/Tissues associated with STK10 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>6 publications with STK10 and Blood
Muscle Antibodies	>1 publications with STK10 and Muscle
Lymph Node Antibodies	>1 publications with STK10 and Lymph Node
Pancreas Antibodies	>1 publications with STK10 and Pancreas
Bone Antibodies	>1 publications with STK10 and Bone
Thymus Antibodies	>1 publications with STK10 and Thymus
Spleen Antibodies	>1 publications with STK10 and Spleen
Skin Antibodies	>1 publications with STK10 and Skin
Bone Marrow Antibodies	>1 publications with STK10 and Bone Marrow
Uncharacterized Tissue Antibodies	>1 publications with STK10 and Uncharacterized Tissue