CADPS Recombinant Protein – Cat# MBS636221

15% SDS-PAGE (3ug)

CAPS, Aa1-189 (CADPS) Recombinant Protein

Name: CADPS Recombinant Protein; CAPS, Aa1-189; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS636221
Price: 685 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS636221

Calcyphosine, also known as CAPS, is a calcium-binding protein containing four EF-hand domains. CAPS is initially identified as thyroid protein p24 that is found in several epithelium and in some cells of the central nervous system. It may play a role in the… More details

$685 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CAPS, aa1-189 (CADPS), Recombinant Protein

Full Product Name

CAPS, aa1-189, Recombinant, Human (Calcyphosin, Calcyphosine, CAPS1, MGC126562)

Product Gene Name

CADPS recombinant protein

Form/Format

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 2mM DTT, 100mM sodium chloride, 10% glycerol.

Purity/Purification

Highly Purified
~95% (SDS-PAGE)

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

~23.1kD

Chromosome Location

Chromosome: 3; NC_000003.11 (62384021..62861064, complement). Location: 3p14.2

OMIM

604667

3D Structure

ModBase 3D Structure for Q9ULU8

Product Categories/Family for CADPS recombinant protein

Molecular Biology; MB-Binding Proteins

Other Notes

Small volumes of CADPS recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CADPS purchase

MBS636221 is a recombinant protein targeting CADPS. Also known as CAPS, aa1-189, Recombinant, Human (Calcyphosin, Calcyphosine, CAPS1, MGC126562).

Additional Details

NCBI/Uniprot data below describe general gene information for CADPS. It may not necessarily be applicable to this product.

NCBI GI #

34452715

NCBI GeneID

8618

NCBI Accession #

NP_003707.2

UniProt Primary Accession #

Q9ULU8

UniProt Secondary Accession #

Q13339; Q6GQQ6; Q8N2Z5; Q8N3M7; Q8NFR0; Q96BC2; A6NF60

UniProt Related Accession #

Q9ULU8

GenBank Nucleotide #

NM_003716.3

NCBI Official Full Name

calcium-dependent secretion activator 1 isoform 1

NCBI Official Synonym Full Names

Ca++-dependent secretion activator

NCBI Official Symbol

CADPS

NCBI Official Synonym Symbols

CAPS; CAPS1; CADPS1

UniProt Protein Name

Calcium-dependent secretion activator 1

UniProt Synonym Protein Names

Calcium-dependent activator protein for secretion 1

Protein Family

Calcium-dependent secretion activator

UniProt Gene Name

CADPS

UniProt Synonym Gene Names

CAPS; CAPS1; KIAA1121; CAPS-1

UniProt Entry Name

CAPS1_HUMAN

NCBI Protein Information

calcium-dependent secretion activator 1; CAPS-1; Ca2+-dependent secretion activator; Ca2+-regulated cytoskeletal protein; Ca2+-dependent activator protein for secretion; calcium-dependent activator protein for secretion 1

NCBI Summary for CADPS

This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008]

UniProt Comments for CADPS

CADPS: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates catecholamine loading of DCVs. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles by acting as a PtdIns(4,5)P2-binding protein that acts at prefusion step following ATP-dependent priming and participates in DCVs-membrane fusion. However, it may also participate in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 3p14.2

Cellular Component: cytoplasmic vesicle membrane; synapse; cytosol; cell junction

Molecular Function: protein binding; metal ion binding; lipid binding; protein kinase binding

Biological Process: catecholamine secretion; protein transport; exocytosis; vesicle organization and biogenesis; synaptic vesicle priming

Research Articles on CADPS

1. Increased level of CADPS protein, human in Schizophrenic patients

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CADPS recombinant protein

Reference Product	PubMed Publications
CAPS2 recombinant protein	>4 publications with CADPS and CAPS2

Diseases associated with CADPS recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with CADPS and Neoplasms
Brain Diseases Antibodies	>1 publications with CADPS and Brain Diseases
Nervous System Diseases Antibodies	>1 publications with CADPS and Nervous System Diseases

Organs/Tissues associated with CADPS recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>7 publications with CADPS and Brain
Nerve Antibodies	>5 publications with CADPS and Nerve
Embryonic Tissue Antibodies	>3 publications with CADPS and Embryonic Tissue
Pituitary Gland Antibodies	>2 publications with CADPS and Pituitary Gland
Testis Antibodies	>1 publications with CADPS and Testis
Ovary Antibodies	>1 publications with CADPS and Ovary
Adrenal Gland Antibodies	>1 publications with CADPS and Adrenal Gland
Lung Antibodies	>1 publications with CADPS and Lung
Eye Antibodies	>1 publications with CADPS and Eye