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CD62L (CD44) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS636290

L-Selectin belongs to a family of divalent cation-dependent carbohydrate-binding glycoproteins or adhesion molecules. Lselectin is expressed constitutively on lymphocytes, monocytes and granulocytes and interacts specifically with carbohydrate groups on… More details

$750 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD62L (CD44), Recombinant Protein
Full Product Name
CD62L, Recombinant, Human (L-Selectin, Leukocyte Endothelial Cell Adhesion Molecule-1, LECAM-1)
Product Gene Name
CD44 recombinant protein
Host
E Coli
Form/Format
Supplied as a liquid in 1X Laemmli Buffer (25mM Tris-HCl, pH 6.8, 50mM DTT, 1% SDS, 0.1% Bromophenol Blue and 2.5% glycerol).
Purity/Purification
Highly Purified
95% (SDS-PAGE). Single band on Western Blot.
Preparation and Storage
-20 degree C
Stability: Store at 4 degree C if entire vial will be used within 1-2 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze-thaw cycles.
Molecular Weight
40,002 Da
Chromosome Location
Chromosome: 15; AC_000172.1 (66454330..66541792). Location: chromosome: 15
3D Structure
ModBase 3D Structure for Q29423

Product Categories/Family for CD44 recombinant protein

Molecular Biology; MB-CD Markers
Application Notes for CD44 recombinant protein
Recombinant Human L-Selectin can be used directly as a positive control in Western blotting, ELISA, immunoprecipitation and other immunological experiments. The biological activity of this product has not yet been tested.

Other Notes

Small volumes of CD44 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD44 purchase

MBS636290 is a recombinant protein targeting CD44. Also known as CD62L, Recombinant, Human (L-Selectin, Leukocyte Endothelial Cell Adhesion Molecule-1, LECAM-1). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CD44. It may not necessarily be applicable to this product.

NCBI GI #
291490675
NCBI GeneID
281057
NCBI Accession #
NP_776438.2
UniProt Primary Accession #
Q29423
UniProt Related Accession #
Q29423
GenBank Nucleotide #
NM_174013.3
NCBI Official Full Name
CD44 antigen
NCBI Official Symbol
CD44
UniProt Protein Name
CD44 antigen
UniProt Synonym Protein Names
Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I
Protein Family
CD44 antigen
UniProt Gene Name
CD44
UniProt Synonym Gene Names
ECMR-III; PGP-1; PGP-I
UniProt Entry Name
CD44_BOVIN
NCBI Protein Information
CD44 antigen; PGP-1; PGP-I; HUTCH-I; ECMR-III; hermes antigen; hyaluronate receptor; phagocytic glycoprotein 1; phagocytic glycoprotein I; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; homing function and Indian blood group system

UniProt Comments for CD44

Function: Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing. May play an important role in invadopodia formation

By similarity.

Subunit structure: Interacts with PKN2

By similarity.

Subcellular location: Membrane; Single-pass type I membrane protein. Note: Colocalizes with actin in membrane protrusions at wounding edges

By similarity.

Tissue specificity: Mesenteric lymph node and liver, not in heart.

Domain: The lectin-like LINK domain is responsible for hyaluronan binding

By similarity.

Post-translational modification: N- and O-glycosylated; contains glycosaminoglycan chondroitin sulfate

By similarity.Phosphorylated on serine residues

By similarity.

Sequence similarities: Contains 1 Link domain.
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Research Articles on CD44

1. CD44 fragmentation, consistent with a signature pattern reported for sequential metalloproteinase/gamma-secretase cleavage of CD44, is a common metabolic feature of chondrocytes that have undergone dedifferentiation in vitro

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CD44 recombinant protein

 Reference Product  PubMed Publications
 CD4 recombinant protein  >1226 publications with CD44 and CD4
 HAS2 recombinant protein  >99 publications with CD44 and HAS2
 MMP9 recombinant protein  >25 publications with CD44 and MMP9
 CD74 recombinant protein  >24 publications with CD44 and CD74
 HYAL2 recombinant protein  >24 publications with CD44 and HYAL2
 TP53 recombinant protein  >22 publications with CD44 and TP53
 HMMR recombinant protein  >18 publications with CD44 and HMMR
 FN1 recombinant protein  >11 publications with CD44 and FN1
 MSN recombinant protein  >6 publications with CD44 and MSN

Pathways associated with CD44 recombinant protein

 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hyaluronan Metabolism Pathway antibodies  Hyaluronan Metabolism Pathway Diagram

Organs/Tissues associated with CD44 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3824 publications with CD44 and Blood
 Lung Antibodies  >707 publications with CD44 and Lung
 Skin Antibodies  >529 publications with CD44 and Skin
 Muscle Antibodies  >456 publications with CD44 and Muscle
 Brain Antibodies  >443 publications with CD44 and Brain
 Intestine Antibodies  >250 publications with CD44 and Intestine
 Adipose Tissue Antibodies  >176 publications with CD44 and Adipose Tissue
 Uterus Antibodies  >115 publications with CD44 and Uterus
 Pancreas Antibodies  >102 publications with CD44 and Pancreas
 Mammary Gland Antibodies  >75 publications with CD44 and Mammary Gland
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