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WDR18 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6363114

WDR18 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes.… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
WDR18, Polyclonal Antibody
Full Product Name
WDR18, CT (WDR18, WD repeat-containing protein 18) (PE)
Product Gene Name
anti-WDR18 antibody
Product Synonym Names
WDR18; WD repeat-containing protein 18
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
47,405 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (984328..994569). Location: 19p13.3
3D Structure
ModBase 3D Structure for Q9BV38
Immunogen
WDR18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-428 amino acids from the C-terminal region of human WDR18.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-WDR18 antibody

Antibodies; WD Repeat Proteins
Applications Tested/Suitable for anti-WDR18 antibody
Western Blot (WB), FLISA
Application Notes for anti-WDR18 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-WDR18 antibody

WDR18 Antibody (C-term) western blot analysis in Neuro-2a cell line lysates (35ug/lane).This demonstrates the WDR18 antibody detected the WDR18 protein (arrow).
Rabbit Anti-WDR18 Polyclonal Antibody – Cat# MBS6363114

Western Blot (WB) of anti-WDR18 antibody

WDR18 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the WDR18 antibody detected the WDR18 protein (arrow).
Rabbit Anti-WDR18 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6363114

Product References and Citations for anti-WDR18 antibody

Rikova, K., et al. Cell 131(6):1190-1203(2007). Andersen, J.S., et al. Nature 433(7021):77-83(2005). Grimwood, J., et al. Nature 428(6982):529-535(2004).

Other Notes

Small volumes of anti-WDR18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WDR18 purchase

MBS6363114 is an antibody targeting WDR18. Also known as WDR18, CT (WDR18, WD repeat-containing protein 18) (PE). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for WDR18. It may not necessarily be applicable to this product.

NCBI GI #
56243583
NCBI GeneID
57418
NCBI Accession #
NP_077005.2
UniProt Primary Accession #
Q9BV38
UniProt Secondary Accession #
O60390; Q9BWR2
UniProt Related Accession #
Q9BV38
GenBank Nucleotide #
NM_024100.3
NCBI Official Full Name
WD repeat-containing protein 18
NCBI Official Synonym Full Names
WD repeat domain 18
NCBI Official Symbol
WDR18
NCBI Official Synonym Symbols
Ipi3; R32184_1
UniProt Protein Name
WD repeat-containing protein 18
Protein Family
WD repeat-containing protein
UniProt Gene Name
WDR18
UniProt Entry Name
WDR18_HUMAN
NCBI Protein Information
WD repeat-containing protein 18; Involved in Processing ITS2 3 homolog

NCBI Summary for WDR18

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
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UniProt Comments for WDR18

WDR18: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: protein binding

Biological Process: multicellular organismal development
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Research Articles on WDR18

1. These data define the PELP1-TEX10-WDR18 complex as a regulator of ribosome biogenesis and suggests that its SUMO-controlled distribution coordinates the rate of ribosome formation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-WDR18 antibody

 Reference Product  PubMed Publications
 TEX10 antibody  >4 publications with WDR18 and TEX10

Diseases associated with anti-WDR18 antibody

 Disease Name  Pubmed Publications
 Neurobehavioral Manifestations Antibodies  >1 publications with WDR18 and Neurobehavioral Manifestations

Organs/Tissues associated with anti-WDR18 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >3 publications with WDR18 and Eye
 Brain Antibodies  >2 publications with WDR18 and Brain
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