ARPC5 Recombinant Protein – Cat# MBS636403

15% SDS-PAGE (3ug)

ARPC5, Aa1-151, His-Tag (ARPC5) Recombinant Protein

Name: ARPC5 Recombinant Protein; MyBioSource
Brand: MyBioSource
SKU: MBS636403
Price: 685 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS636403

p16-ARC, also known as ARPC5, is a 151 amino acid subunit of the Arp2/3 complex. Thought to play a role in maintaining the integrity of Arp2/3, ARPC5 is a substrate for MAPKAPK-2 which, through phosphorylation of ARPC5, may participate in Arp2/3 regulatory… More details

$685 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ARPC5, aa1-151, His-tag, Recombinant Protein

Full Product Name

ARPC5, Recombinant, Human, aa1-151, His-tag (Actin-related Protein 2/3 Complex Subunit 5 Protein, Arp2/3 Complex 16kD Subunit 2, ARC16-2)

Product Gene Name

ARPC5 recombinant protein

Sequence

MGSSHHHHHH SSGLVPRGSH MSKNTVSSAR FRKVDVDEYD ENKFVDEEDG GDGQAGPDEG EVDSCLRQGN MTAALQAALK NPPINTKSQA VKDRAGSIVL KVLISFKAND IEKAVQSLDK NGVDLLMKYI YKGFESPSDN SSAMLLQWHE KALAAGGVGS IVRVLTARKT V

Form/Format

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8, 1mM DTT, 0.1M sodium chloride, 50% glycerol.

Purity/Purification

Highly Purified
~90% (SDS-PAGE)

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

~18.4kD

Chromosome Location

Chromosome: 1; NC_000001.10 (183595328..183605076, complement). Location: 1q25.3

OMIM

604227

3D Structure

ModBase 3D Structure for O15511

Product Categories/Family for ARPC5 recombinant protein

Molecular Biology; MB-Actin Related Proteins

Other Notes

Small volumes of ARPC5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARPC5 purchase

MBS636403 is a recombinant protein targeting ARPC5. Also known as ARPC5, Recombinant, Human, aa1-151, His-tag (Actin-related Protein 2/3 Complex Subunit 5 Protein, Arp2/3 Complex 16kD Subunit 2, ARC16-2).

Additional Details

NCBI/Uniprot data below describe general gene information for ARPC5. It may not necessarily be applicable to this product.

NCBI GI #

394025704

NCBI GeneID

10092

NCBI Accession #

NP_001257368.1

UniProt Primary Accession #

O15511

UniProt Secondary Accession #

Q6PG42; A6NEC4

UniProt Related Accession #

O15511

GenBank Nucleotide #

NM_001270439.1

NCBI Official Full Name

actin-related protein 2/3 complex subunit 5 isoform 2

NCBI Official Synonym Full Names

actin related protein 2/3 complex, subunit 5, 16kDa

NCBI Official Symbol

ARPC5

NCBI Official Synonym Symbols

ARC16; p16-Arc; dJ127C7.3

UniProt Protein Name

Actin-related protein 2/3 complex subunit 5

UniProt Synonym Protein Names

Arp2/3 complex 16 kDa subunit

Protein Family

Actin-related protein 2/3 complex

UniProt Gene Name

ARPC5

UniProt Synonym Gene Names

ARC16; p16-ARC

UniProt Entry Name

ARPC5_HUMAN

NCBI Protein Information

actin-related protein 2/3 complex subunit 5; arp2/3 complex 16 kDa subunit; Arp2/3 protein complex subunit p16

NCBI Summary for ARPC5

This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

UniProt Comments for ARPC5

ARPC5: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Belongs to the ARPC5 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 1q25.3

Cellular Component: Arp2/3 protein complex; focal adhesion; cell projection; cytoplasm; cytosol; actin cytoskeleton

Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton

Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; cell motility; actin cytoskeleton organization and biogenesis

Research Articles on ARPC5

1. Levels of ARPC5 expression were significantly higher in invasive cancer cells and gene expression was directly regulated by miR-133a.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ARPC5 recombinant protein

Reference Product	PubMed Publications
ARPC2 recombinant protein	>6 publications with ARPC5 and ARPC2
ARPC3 recombinant protein	>3 publications with ARPC5 and ARPC3
ACTR3 recombinant protein	>2 publications with ARPC5 and ACTR3
WASF1 recombinant protein	>1 publications with ARPC5 and WASF1
ACTR2 recombinant protein	>1 publications with ARPC5 and ACTR2

Pathways associated with ARPC5 recombinant protein

Products by Pathway	Pathway Diagram
B Cell Receptor Signaling Pathway antibodies	B Cell Receptor Signaling Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
CDC42 Signaling Events Pathway antibodies	CDC42 Signaling Events Pathway Diagram
ErbB1 Downstream Signaling Pathway antibodies	ErbB1 Downstream Signaling Pathway Diagram
Fc Gamma R-mediated Phagocytosis Pathway antibodies	Fc Gamma R-mediated Phagocytosis Pathway Diagram
Fc Gamma R-mediated Phagocytosis Pathway antibodies	Fc Gamma R-mediated Phagocytosis Pathway Diagram
Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies	Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Diseases associated with ARPC5 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with ARPC5 and Neoplasms
Lung Neoplasms Antibodies	>1 publications with ARPC5 and Lung Neoplasms

Organs/Tissues associated with ARPC5 recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>3 publications with ARPC5 and Muscle
Thymus Antibodies	>3 publications with ARPC5 and Thymus
Brain Antibodies	>2 publications with ARPC5 and Brain
Spleen Antibodies	>1 publications with ARPC5 and Spleen
Liver Antibodies	>1 publications with ARPC5 and Liver
Vascular Antibodies	>1 publications with ARPC5 and Vascular
Lung Antibodies	>1 publications with ARPC5 and Lung
Blood Antibodies	>1 publications with ARPC5 and Blood
Testis Antibodies	>1 publications with ARPC5 and Testis
Nerve Antibodies	>1 publications with ARPC5 and Nerve