Fkbp1a /FKBP12, 1-108aa Recombinant Protein

FK506 binding protein 1a, also known as FKBP12, belongs to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. Recombinant human FKBP12, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Small volumes of FKBP1a /FKBP12, 1-108aa recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS636490 is a recombinant protein targeting FKBP1a /FKBP12, 1-108aa. Also known as FKBP1a /FKBP12, 1-108aa, Recombinant, Human (FK506 binding protein 1a, 12kD, PPIase FKBP1A, Rotamase, FKBP1, PKC12). Host: E Coli.