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Fibroblast Activation Protein Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS636509

Human FAP (GenBank Accession No. NM_004460), (aa29-end) with C-terminal His tag, expressed in a Baculovirus infected Sf9 cell expression system. Fibroblast Activation Protein (FAP) is a cell surface glycoprotein of reactive human fibroblasts. Among the normal… More details

$1195 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fibroblast Activation Protein, Active Protein
Full Product Name
Fibroblast Activation Protein, Recombinant, Human (FAP)
Host
Sf9 insect cells
Form/Format
Supplied as a liquid in 40mM Tris-HCl, pH 8.0, 110mM sodium chloride, 2.2mM potassium chloride, 200mM imidazole, 3mM DTT, 20% glycerol.
Purity/Purification
Highly Purified
~70%
Preparation and Storage
Aliquot to avoid repeated freezing and thawing and store at -70 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for 6 months.
Molecular Weight
85.5kD
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Specific Activity
~10pmol/min/ug
Assay Buffer
50mM Tris pH 7.5, 10mM MgCl2, 1mM MnCl2, 20uM substrate (A-P-AMC)

Product Categories/Family for Fibroblast Activation Protein active protein

Molecular Biology; MB-Carbohydrates; Glycoproteins
Application Notes for Fibroblast Activation Protein active protein
Suitable for use in the study of enzyme kinetics, screening inhibitors and selectivity profiling.

Testing Data of Fibroblast Activation Protein active protein

specific activity
Active Protein – Cat# MBS636509

SDS-Page of Fibroblast Activation Protein active protein

10% SDS-PAGE Coomassie staining using 5ug of F4208-50H in lane 1. Lane 2: Protein Marker
Active Protein, SDS-Page – Cat# MBS636509

Other Notes

Small volumes of Fibroblast Activation Protein active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Fibroblast Activation Protein purchase

MBS636509 is an active protein targeting Fibroblast Activation Protein. Also known as Fibroblast Activation Protein, Recombinant, Human (FAP). Host: Sf9 insect cells.

Additional Details

NCBI/Uniprot data below describe general gene information for Fibroblast Activation Protein. It may not necessarily be applicable to this product.

NCBI GI #
1888316
NCBI Accession #
AAB49652.1
NCBI Official Full Name
fibroblast activation protein
Protein Family
Prolyl endopeptidase

UniProt Comments for Fibroblast Activation Protein

FAP: In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers. Belongs to the peptidase S9B family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.21.26; Membrane protein, integral; EC 3.4.14.5; Protease

Chromosomal Location of Human Ortholog: 2q23

Cellular Component: extracellular space; focal adhesion; cell surface; lamellipodium; apical part of cell; cytoplasm; integral to membrane; plasma membrane

Molecular Function: peptidase activity; integrin binding; protein dimerization activity; protein binding; protein homodimerization activity; protease binding; serine-type peptidase activity; dipeptidyl-peptidase activity; metalloendopeptidase activity; serine-type endopeptidase activity; endopeptidase activity

Biological Process: proteolysis involved in cellular protein catabolic process; endothelial cell migration; angiogenesis; proteolysis; cell adhesion; regulation of fibrinolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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