LEPR Active Protein

Name: LEPR Active Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS636524
Price: 530 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS636524

Leptin receptor (LEPR), also known as OB-R and B219, is a single transmembrane-domain receptor of the cytokine receptor family. Leptin receptor exists as homodimer and binds Leptin with high affinity, thus mediates the biological function of the… More details

$530 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LEPR, Active Protein

Full Product Name

LEPR, Recombinant, Human (Leptin Receptor, LEP-R, HuB219, OB Receptor, OB-R, CD295, DB, OBR)

Sequence

A DNA sequence encoding the extracellu lar domian (Met 1-Asp 839) of human leptin receptor (Np_002294 .2) was expressed and fused with a C-terminal polyhistid ine tag. Predict NT sequence is Phe 22.

Host

Human Cells

Form/Format

Supplied as a lyophilized powder from PBS, pH 7.4

Purity/Purification

Highly Purified
~98% (SDS-PAGE, HPLC)

Specificity

Leptin, LERP is expressed at high levels in hematopoietic stem cells, lymphohematopoietic cell lines, as well as adult reproductive organs. Several isoforms of LEPR have been identified, and LEPR Structurally contains two hemopoietin receptor domains, a fibronectin type III domain and a WSZWS domain within the extracellular region.

Preparation and Storage

Lyophilized powder may be stored at -70 degree C. Stable for 12 months at -20 degree C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -70 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

~95kD

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio.

Molecular Mass

The recombinant human LEPR consists of 829aa and has a predicted molecular mass of 95kD. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhLEPR is ~130 to 140 kD due to glycosylation.

Product Categories/Family for LEPR active protein

Molecular Biology; MB-Obesity

Other Notes

Small volumes of LEPR active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LEPR purchase

MBS636524 is an active protein targeting LEPR. Also known as LEPR, Recombinant, Human (Leptin Receptor, LEP-R, HuB219, OB Receptor, OB-R, CD295, DB, OBR). Host: Human Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for LEPR. It may not necessarily be applicable to this product.

NCBI GI #

82569700

NCBI Accession #

ABB83472.1

NCBI Official Full Name

LEPR

Protein Family

Leptin receptor

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.