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ZHX2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6365325

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ZHX2, Polyclonal Antibody
Full Product Name
ZHX2, NT (ZHX2, AFR1, KIAA0854, RAF, Zinc fingers and homeoboxes protein 2, Alpha-fetoprotein regulator 1, Regulator of AFP, Zinc finger and homeodomain protein 2) (PE)
Product Gene Name
anti-ZHX2 antibody
Product Synonym Names
ZHX2; AFR1; KIAA0854; RAF; Zinc fingers and homeoboxes protein 2; Alpha-fetoprotein regulator 1; Regulator of AFP; Zinc finger and homeodomain protein 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
92,307 Da
OMIM
609185
3D Structure
ModBase 3D Structure for Q9Y6X8
Immunogen
ZHX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 104-131 amino acids selected from the N-terminal region of human ZHX2.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-ZHX2 antibody

Antibodies; Transcription Factors; Zinc; Ring; Homeobox
Applications Tested/Suitable for anti-ZHX2 antibody
Western Blot (WB), FLISA
Application Notes for anti-ZHX2 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ZHX2 antibody

ZHX2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ZHX2 antibody detected the ZHX2 protein (arrow).
Rabbit Anti-ZHX2 Polyclonal Antibody – Cat# MBS6365325

Immunofluorescence (IF) of anti-ZHX2 antibody

Fluorescent confocal image of A549 cell stained with ZHX2 Antibody (N-term).A549 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with ZHX2 primary antibody (1:25, 1 h at 37 degree C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37 degree C).Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37 degree C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). ZHX2 immunoreactivity is localized to Nucleus significantly and Cytoplasm weakly.
Rabbit Anti-ZHX2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS6365325

Product References and Citations for anti-ZHX2 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Xu, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(5):2136-2140(2010). Trynka, G., et al. Gut 58(8):1078-1083(2009). Shen, H., et al. J. Cell. Mol. Med. 12 (6B), 2772-2780 (2008): Hu, S., et al. Neoplasma 54(3):207-211(2007).

Other Notes

Small volumes of anti-ZHX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZHX2 purchase

MBS6365325 is an antibody targeting ZHX2. Also known as ZHX2, NT (ZHX2, AFR1, KIAA0854, RAF, Zinc fingers and homeoboxes protein 2, Alpha-fetoprotein regulator 1, Regulator of AFP, Zinc finger and homeodomain protein 2) (PE). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZHX2. It may not necessarily be applicable to this product.

NCBI GI #
7662342
NCBI GeneID
22882
NCBI Accession #
NP_055758.1
UniProt Primary Accession #
Q9Y6X8
UniProt Related Accession #
Q9Y6X8
GenBank Nucleotide #
NM_014943.3
NCBI Official Full Name
zinc fingers and homeoboxes protein 2
NCBI Official Synonym Full Names
zinc fingers and homeoboxes 2
NCBI Official Symbol
ZHX2
NCBI Official Synonym Symbols
RAF; AFR1
UniProt Protein Name
Zinc fingers and homeoboxes protein 2
UniProt Synonym Protein Names
Alpha-fetoprotein regulator 1; AFP regulator 1; Regulator of AFP; Zinc finger and homeodomain protein 2
Protein Family
Zinc fingers and homeoboxes protein
UniProt Gene Name
ZHX2
UniProt Synonym Gene Names
AFR1; KIAA0854; RAF; AFP regulator 1
UniProt Entry Name
ZHX2_HUMAN
NCBI Protein Information
zinc fingers and homeoboxes protein 2; AFP regulator 1; regulator of AFP; transcription factor ZHX2; alpha-fetoprotein regulator 1; zinc-fingers and homeoboxes 2; zinc finger and homeodomain protein 2

Research Articles on ZHX2

1. simultaneous application of ZFN and rescue DNA induced gene repair of the disease-causing mutation on the genomic level, resulting in recovery of protein expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ZHX2 antibody

 Reference Product  PubMed Publications
 VEGFA antibody  >1 publications with ZHX2 and VEGFA

Pathways associated with anti-ZHX2 antibody

 Products by Pathway  Pathway Diagram
 Hypothetical Network For Drug Addiction Pathway antibodies  Hypothetical Network For Drug Addiction Pathway Diagram

Diseases associated with anti-ZHX2 antibody

 Disease Name  Pubmed Publications
 Carcinoma, Hepatocellular Antibodies  >12 publications with ZHX2 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >8 publications with ZHX2 and Liver Neoplasms
 Liver Diseases Antibodies  >8 publications with ZHX2 and Liver Diseases
 Immune System Diseases Antibodies  >6 publications with ZHX2 and Immune System Diseases
 Disease Models, Animal Antibodies  >3 publications with ZHX2 and Disease Models, Animal
 Kidney Diseases Antibodies  >3 publications with ZHX2 and Kidney Diseases
 Proteinuria Antibodies  >2 publications with ZHX2 and Proteinuria
 Autoimmune Diseases Antibodies  >2 publications with ZHX2 and Autoimmune Diseases
 Neoplasms, Experimental Antibodies  >1 publications with ZHX2 and Neoplasms, Experimental
 Brain Diseases Antibodies  >1 publications with ZHX2 and Brain Diseases

Organs/Tissues associated with anti-ZHX2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >16 publications with ZHX2 and Liver
 Bone Antibodies  >3 publications with ZHX2 and Bone
 Kidney Antibodies  >3 publications with ZHX2 and Kidney
 Bone Marrow Antibodies  >2 publications with ZHX2 and Bone Marrow
 Brain Antibodies  >2 publications with ZHX2 and Brain
 Lymph Antibodies  >1 publications with ZHX2 and Lymph
 Lymph Node Antibodies  >1 publications with ZHX2 and Lymph Node
 Prostate Antibodies  >1 publications with ZHX2 and Prostate
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