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ZNF259 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6366019

ZNF259 may be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ZNF259, Polyclonal Antibody
Full Product Name
ZNF259, CT (ZNF259, ZPR1, Zinc finger protein ZPR1, Zinc finger protein 259) (AP)
Product Gene Name
anti-ZNF259 antibody
Product Synonym Names
ZNF259; ZPR1; Zinc finger protein ZPR1; Zinc finger protein 259
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
50,925 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (116649276..116658739, complement). Location: 11q23.3
OMIM
603901
3D Structure
ModBase 3D Structure for O75312
Immunogen
ZNF259 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-434 amino acids from the C-terminal region of human ZNF259.
Conjugate
AP
Note
Preservative Free

Product Categories/Family for anti-ZNF259 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger
Applications Tested/Suitable for anti-ZNF259 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ZNF259 antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ZNF259 antibody

ZNF259 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the ZNF259 antibody detected the ZNF259 protein (arrow).
Rabbit Anti-ZNF259 Polyclonal Antibody – Cat# MBS6366019

Western Blot (WB) of anti-ZNF259 antibody

ZNF259 Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the ZNF259 antibody detected the ZNF259 protein (arrow).
Rabbit Anti-ZNF259 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6366019

Product References and Citations for anti-ZNF259 antibody

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Johansen, C.T., et al. Nat. Genet. 42(8):684-687(2010). Suchindran, S., et al. PLoS Genet. 6 (4), E1000928 (2010): Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Kathiresan, S., et al. Nat. Genet. 41(1):56-65(2009).

Other Notes

Small volumes of anti-ZNF259 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZNF259 purchase

MBS6366019 is an antibody targeting ZNF259. Also known as ZNF259, CT (ZNF259, ZPR1, Zinc finger protein ZPR1, Zinc finger protein 259) (AP). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZNF259. It may not necessarily be applicable to this product.

NCBI GI #
4508021
NCBI GeneID
8882
NCBI Accession #
NP_003895.1
UniProt Primary Accession #
O75312
UniProt Secondary Accession #
Q2TAA0
UniProt Related Accession #
O75312
GenBank Nucleotide #
NM_003904.3
NCBI Official Full Name
zinc finger protein ZPR1
NCBI Official Synonym Full Names
zinc finger protein 259
NCBI Official Symbol
ZNF259
NCBI Official Synonym Symbols
ZPR1
UniProt Protein Name
Zinc finger protein ZPR1
UniProt Synonym Protein Names
Zinc finger protein 259
UniProt Gene Name
ZPR1
UniProt Synonym Gene Names
ZNF259
UniProt Entry Name
ZPR1_HUMAN
NCBI Protein Information
zinc finger protein ZPR1

UniProt Comments for ZNF259

ZNF259: May be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. Binds to the EGF and PDGF receptors. Binds to the elongation factor 1-alpha EF1A. Component of an import snRNP complex composed of KPNB1, SNUPN, SMN1 and ZNF259. Belongs to the ZPR1 family.

Protein type: Nucleolus; Cell cycle regulation

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: nucleoplasm; Cajal body; growth cone; cell soma; perinuclear region of cytoplasm; axon; cytoplasm; nucleolus; perikaryon; SMN complex; nucleus

Molecular Function: protein binding; zinc ion binding; translation initiation factor binding; receptor tyrosine kinase binding

Biological Process: cell proliferation; regulation of myelination; trophectodermal cell proliferation; positive regulation of protein import into nucleus; spinal cord development; RNA splicing; DNA endoreduplication; Cajal body organization and biogenesis; microtubule cytoskeleton organization and biogenesis; mRNA processing; signal transduction; positive regulation of RNA splicing; positive regulation of growth; inner cell mass cell proliferation
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Research Articles on ZNF259

1. Significant associations of two SNPs (rs964184 and rs12286037) from ZNF259 with triglyceride levels in an Asian Indian cohort.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ZNF259 antibody

 Reference Product  PubMed Publications
 EGFR antibody  >2 publications with ZNF259 and EGFR
 GEMIN7 antibody  >1 publications with ZNF259 and GEMIN7
 EEF1A1 antibody  >1 publications with ZNF259 and EEF1A1
 NPAT antibody  >1 publications with ZNF259 and NPAT

Pathways associated with anti-ZNF259 antibody

 Products by Pathway  Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram

Diseases associated with anti-ZNF259 antibody

 Disease Name  Pubmed Publications
 Atrophy Antibodies  >8 publications with ZNF259 and Atrophy

Organs/Tissues associated with anti-ZNF259 antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >2 publications with ZNF259 and Embryonic Tissue
 Blood Antibodies  >1 publications with ZNF259 and Blood
 Eye Antibodies  >1 publications with ZNF259 and Eye
 Testis Antibodies  >1 publications with ZNF259 and Testis
 Brain Antibodies  >1 publications with ZNF259 and Brain
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