PRAK, Unactive (PRAK) Active Protein

p38-regulated/activated protein kinase (PRAK) is a 471 amino acid protein with 20-30% sequence identity to the known MAP kinase-regulated protein kinases RSK1/2/3, MNK1/2, and MAPKAP-K2/3. PRAK is activated by stress-related extra-cellular stimuli. The regulatory phosphorylation site of PRAK is Thr182, which is phosphorylated by p38 alpha and p38 beta in vitro. Activated PRAK specifically phosphorylates HSP27 at its physiologically relevant sites in vitro.

Recombinant full-length human PRAK with an N-terminal His-tag, expressed in Sf9 cells.
Mr ~54kD

Small volumes of PRAK, unactive active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS636621 is an active protein targeting PRAK, unactive. Also known as PRAK, unactive, Recombinant, Human (p38 Regulated Activated Protein Kinase). Host: Recombinant, human.