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Rank:fc (RANK) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS636903

RANK (TRANCE-R; CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells. More details

$605 / 0.05 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RANK:Fc, Active Protein
Full Product Name
RANK:Fc, Recombinant, Human (TRANCE-R, TNFRSF11A, ODFR, Osteoclast Differentiation Factor Receptor, CD265)
Sequence
Human RANK (aa 29-213) is fused at the C-terminus to the Fc portion of human IgG1.
Host
Human, HEK 293 cells
Form/Format
Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2. Reconstitute with 50ul of sterile ddH20. Recognizes human and mouse RANKL.
Purity/Purification
Highly Purified
>95% (SDS-PAGE)
Concentration
~1 mg/ml (after reconstitution) (lot specific)
Preparation and Storage
Lyophilized powder may be stored at -20°C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
~55kD (SDS-PAGE)
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Inhibits human rhsRANKL biological functions.

Other Notes

Small volumes of RANK:Fc active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RANK:Fc purchase

MBS636903 is an active protein targeting RANK:Fc. Also known as RANK:Fc, Recombinant, Human (TRANCE-R, TNFRSF11A, ODFR, Osteoclast Differentiation Factor Receptor, CD265). Host: Human, HEK 293 cells.
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