SPG21, 1-308 Aa (SPG21) Recombinant Protein

Spastic paraplegia 21(SPG21), also known as Maspardin, binds to the hydrophobic C-terminal amino acids of CD4 and may play a role as a negative regulatory factor in CD4-depenent T-cell activation. This protein is widely expressed in various tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Mutations in SPG21 cause Mast syndrome, an autosomal-recessive complicated form of hereditary spastic paraplegia characterized by dementia, thin corpus callosum and white matter abnormalities. Recombinant human SPG21 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Small volumes of SPG21, 1-308 aa recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS636941 is a recombinant protein targeting SPG21, 1-308 aa. Also known as SPG21, 1-308 aa, Recombinant, Human (Spastic paraplegia 21 isoform a, ACP33, BM-019, GL010, Maspardin, MAST, Acid cluster protein 33, ACP33, BM-019, GL010, Maspardin, MASPARDIN, MAST, Spastic paraplegia 21 autosomal recessive Mast syndrome protein). Host: E Coli.