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DR4 Recombinant (DR4) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637001

TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain, " which can activate the cell's apoptotic machinery. These receptors are activated by binding to either membrane… More details

$480 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DR4 Recombinant, Active Protein
Full Product Name
DR4 Recombinant, Human (TRAIL R1, TRAIL Receptor1, Death Receptor4)
Sequence
MSGTGAAAAT PSKVWGSSAG RIEPRGGGRG ALPTSMGQHG PSARARAGRA PGPRPAREAS PRLRVHKTFK FVVVGVLLQV VPSSAATIKL HDQSIGTQQW EHSPLGELCP PGSHRSERPG ACNRCTEGVG YTNASQQLFA CLPCTACKSD EEERSPCTTT RNTACQCKPG TFRNDNSAEM CRKCSTGCPR GMVKVKDCTP WSDIECVHKE SGNGHN
Host
E Coli
Form/Format
Supplied as a lyophilized powder. No additives. Reconsitute in sterile ddH2O to a concentration of 0.1-1mg/ml, which can then be diluted into other aqueous solutions. Do not vortex.
Purity/Purification
Highly Purified
Purity
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Reconstitute with sterile ddH2O, 0.1% BSA or HSA. Aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
22.7kD
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
The specific activity as determined by its inhibitory effect of IL-8 production in human PBMC (peripheral blood mononuclear cells) by human sTRAIL/Apo2L. 95% inhibition (100ng/ml of sTRAIL/Apo2L) was reached using a concentration of 100ng/ml of sTRAIL Receptor-1.
Country of Origin
USA

Other Notes

Small volumes of DR4 Recombinant active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DR4 Recombinant purchase

MBS637001 is an active protein targeting DR4 Recombinant. Also known as DR4 Recombinant, Human (TRAIL R1, TRAIL Receptor1, Death Receptor4). Host: E Coli.
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