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Usher Syndrome 1c (USHBP1) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637145

Harmonin, product encoded by USH1c gene, is a scaffold protein that functions in the assembly of Usher protein complexes. Usher syndrome type I caused by mutations in USH1C is an autosomal recessive sensory defect involving congenital profound sensorineural… More details

$685 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Usher Syndrome 1C (USHBP1), Recombinant Protein
Full Product Name
Usher Syndrome 1C, Recombinant, Human (Autosomal Recessive, Severe, Protein, USH 1C, USH1C, USH-1C, Ush1cpst, AIE 75, Autoimmune Enteropathy Related Antigen AIE 75, Deafness Autosomal Recessive 18, DFNB18, Harmonin, NY-CO-37, NY-CO-38, PDZ-45, PDZ73, Rena
Product Synonym Names
Usher Syndrome 1C, Recombinant, Human (Autosomal Recessive, Severe, Protein, USH 1C, USH1C, USH-1C, Ush1cpst, AIE 75, Autoimmune Enteropathy Related Antigen AIE 75, Deafness Autosomal Recessive 18, DFNB18, Harmonin, NY-CO-37, NY-CO-38, PDZ-45, PDZ73, Rena
Sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMDR KVAREFRHKV DFLIENDAEK DYLYDVLRMY HQTMDVAVLV GDLKLVINEP SRLPLFDAIR PLIPLKHQVE YDQLTPRRSR KLKEVRLDRL HPEGLGLSVR GGLEFGCGLF ISHLIKGGQA DSVGLQVGDE IVRINGYSIS SCTHEEVINL IRTKKTVSIK VRHIGLIPVK SSPDEPLTWQ YVDQFVSESG GVRGSLGSPG NRENKEKKVF ISLVGSRGLG CSISSGPIQK PGIFISHVKP GSLSAEVGLE IGDQIVEVNG VDFSNLDHKE GRELFMTDRE RLAEARQREL QRQELLMQKR LAMESNKILQ EQQEMERQRR KEIAQKAAEE NERYRKEMEQ IVEEEEKFKK QWEEDWGSKE QLLLPKTITA EVHPVPLRKP KYDQGVEPEL EPADDLDGGT EEQGEQDFRK YEEGFDPYSM FTPEQIMGKD VRLLRIKKEG SLDLALEGGV DSPIGKVVVS AVYERGAAER HGGIVKGDEI MAINGKIVTD YTLAEADAAL QKAWNQGGDW IDLVVAVCPP KEYDDELTFF .
Form/Format
Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 20% glycerol.
Purity/Purification
Purified
~ 95% by SDS-PAGE.
Preparation and Storage
For long-term storage, aliquot and store at -20 degree C/-70 degree C. Aliquots are stable for at least 6 months at -20 degree C/-70 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
64.6kD
Chromosome Location
Chromosome: 19; NC_000019.9 (17360537..17375605, complement). Location: 19p13
OMIM
611810
3D Structure
ModBase 3D Structure for Q8N6Y0

SDS-Page of USHBP1 recombinant protein

15% SDS-PAGE (3ug)
USHBP1 Recombinant Protein – Cat# MBS637145

Other Notes

Small volumes of USHBP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for USHBP1 purchase

MBS637145 is a recombinant protein targeting USHBP1. Also known as Usher Syndrome 1C, Recombinant, Human (Autosomal Recessive, Severe, Protein, USH 1C, USH1C, USH-1C, Ush1cpst, AIE 75, Autoimmune Enteropathy Related Antigen AIE 75, Deafness Autosomal Recessive 18, DFNB18, Harmonin, NY-CO-37, NY-CO-38, PDZ-45, PDZ73, Rena.

Additional Details

NCBI/Uniprot data below describe general gene information for USHBP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Usher syndrome 1C binding protein 1, isoform CRA_b
NCBI Official Synonym Full Names
Usher syndrome 1C binding protein 1
NCBI Official Symbol
USHBP1
NCBI Official Synonym Symbols
MCC2; AIEBP
UniProt Protein Name
Usher syndrome type-1C protein-binding protein 1
UniProt Synonym Protein Names
AIE-75-binding protein; MCC-2; Mutated in colon cancer protein 2
UniProt Gene Name
USHBP1
UniProt Synonym Gene Names
AIEBP; MCC2; USH1C-binding protein 1
UniProt Entry Name
USBP1_HUMAN
NCBI Protein Information
Usher syndrome type-1C protein-binding protein 1; MCC-2; AIE-75-binding protein; USH1C-binding protein 1; AIE-75 binding protein protein; mutated in colon cancer protein 2

UniProt Comments for USHBP1

USHBP1: Belongs to the MCC family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19p13

Molecular Function: protein binding; PDZ domain binding

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with USHBP1 recombinant protein

Organs/Tissues associated with USHBP1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with USHBP1 and Brain
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