Human TST Recombinant Protein – Cat# MBS637172

Thiosulfate Sulfurtransferase Human, Aa1-297 (TST) Human Recombinant Protein

Name: TST Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS637172
Price: 755 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637172

Thiosulfate sulfurtransferase (TST), also known as Rhodanese, is a mitochondrial enzyme that involved in cyanide detoxification and the modification of sulfur-containing enzymes. This protein contains two highly conservative domains, known as rhodanese… More details

$755 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Thiosulfate sulfurtransferase Human, aa1-297 (TST), Recombinant Protein

Full Product Name

Thiosulfate sulfurtransferase, Recombinant Human, aa1-297 (TST)

Product Gene Name

TST recombinant protein

Sequence

MGSSHHHHHH SSGLVPRGSH MVHQVLYRAL VSTKWLAESI RTGKLGPGLR VLDASWYSPG TREARKEYLE RHVPGASFFD IEECRDTASP YEMMLPSEAG FAEYVGRLGI SNHTHVVVYD GEHLGSFYAP RVWWMFRVFG HRTVSVLNGG FRNWLKEGHP VTSEPSRPEP AVFKATLDRS LLKTYEQVLE NLESKRFQLV DSRSQGRFLG TEPEPDAVGL DSGHIRGAVN MPFMDFLTED GFEKGPEELR ALFQTKKVDL SQPLIATCRK GVTACHVALA AYLCGKPDVA VYDGSWSEWF RRAPPESRVS QGKSEKA

Species Reactivity

Human

Form/Format

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol.

Purity/Purification

Affinity Purified
~95% (SDS-PAGE) Purified by immunoaffinity chromatography.

Preparation and Storage

Aliquot to avoid repeated freezing and thawing and freeze at -70 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.

Molecular Weight

35.6 kDa

Chromosome Location

Chromosome: 22; NC_000022.10 (37406900..37416224, complement). Location: 22q13.1

OMIM

180370

3D Structure

ModBase 3D Structure for Q16762

Product Categories/Family for TST recombinant protein

Molecular Biology; MB-Enzymes

Other Notes

Small volumes of TST recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TST purchase

MBS637172 is a recombinant protein targeting TST. Also known as Thiosulfate sulfurtransferase, Recombinant Human, aa1-297 (TST). Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for TST. It may not necessarily be applicable to this product.

NCBI GI #

395394071

NCBI GeneID

7263

NCBI Accession #

NP_001257412.1

UniProt Primary Accession #

Q16762

UniProt Secondary Accession #

Q6IB06; B3KRM1

UniProt Related Accession #

Q16762

GenBank Nucleotide #

NM_001270483.1

NCBI Official Full Name

thiosulfate sulfurtransferase

NCBI Official Synonym Full Names

thiosulfate sulfurtransferase (rhodanese)

NCBI Official Symbol

TST

NCBI Official Synonym Symbols

RDS

UniProt Protein Name

Thiosulfate sulfurtransferase

UniProt Synonym Protein Names

Rhodanese

Protein Family

Toxic shock syndrome toxin

UniProt Gene Name

TST

UniProt Entry Name

THTR_HUMAN

NCBI Protein Information

thiosulfate sulfurtransferase

NCBI Summary for TST

This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

UniProt Comments for TST

TST: Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity. Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA.

Protein type: Mitochondrial; Transferase; EC 2.8.1.1

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: extracellular space; mitochondrion; mitochondrial matrix; mitochondrial inner membrane

Molecular Function: thiosulfate sulfurtransferase activity; 5S rRNA binding

Biological Process: cyanate catabolic process; epithelial cell differentiation; sulfur amino acid metabolic process; rRNA transport; sulfur amino acid catabolic process

Research Articles on TST

1. Loss of Thiosulfate Sulfurtransferase is associated with decreased mucosal sulfide detoxification capacity in patients with Crohn's disease

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TST recombinant protein

Reference Product	PubMed Publications
ETHE1 recombinant protein	>3 publications with TST and ETHE1

Pathways associated with TST recombinant protein

Products by Pathway	Pathway Diagram
Cysteine And Methionine Metabolism Pathway antibodies	Cysteine And Methionine Metabolism Pathway Diagram
Cysteine And Methionine Metabolism Pathway antibodies	Cysteine And Methionine Metabolism Pathway Diagram
Degradation Of Cysteine And Homocysteine Pathway antibodies	Degradation Of Cysteine And Homocysteine Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
Sulfide Oxidation To Sulfate Pathway antibodies	Sulfide Oxidation To Sulfate Pathway Diagram
Sulfur Amino Acid Metabolism Pathway antibodies	Sulfur Amino Acid Metabolism Pathway Diagram
Sulfur Metabolism Pathway antibodies	Sulfur Metabolism Pathway Diagram
Sulfur Metabolism Pathway antibodies	Sulfur Metabolism Pathway Diagram
Sulfur Relay System Pathway antibodies	Sulfur Relay System Pathway Diagram

Diseases associated with TST recombinant protein

Disease Name	Pubmed Publications
Necrosis Antibodies	>124 publications with TST and Necrosis
Neoplasms Antibodies	>76 publications with TST and Neoplasms
Cardiovascular Diseases Antibodies	>71 publications with TST and Cardiovascular Diseases
Inflammation Antibodies	>70 publications with TST and Inflammation
Kidney Diseases Antibodies	>52 publications with TST and Kidney Diseases
Heart Diseases Antibodies	>38 publications with TST and Heart Diseases
Weight Loss Antibodies	>20 publications with TST and Weight Loss
Hypertension Antibodies	>19 publications with TST and Hypertension
Carcinoma Antibodies	>18 publications with TST and Carcinoma
Liver Diseases Antibodies	>18 publications with TST and Liver Diseases

Organs/Tissues associated with TST recombinant protein

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>1286 publications with TST and Skin
Brain Antibodies	>268 publications with TST and Brain
Lung Antibodies	>248 publications with TST and Lung
Muscle Antibodies	>98 publications with TST and Muscle
Eye Antibodies	>80 publications with TST and Eye
Nerve Antibodies	>70 publications with TST and Nerve
Kidney Antibodies	>60 publications with TST and Kidney
Heart Antibodies	>58 publications with TST and Heart
Liver Antibodies	>53 publications with TST and Liver
Lymph Node Antibodies	>21 publications with TST and Lymph Node