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FGF-23:fc (FGF) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637209

FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates… More details

$545 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FGF-23:Fc, Active Protein
Full Product Name
FGF-23:Fc, Recombinant, Human (Fibroblast Growth Factor 23, Tumor-derived Hypophosphatemia-inducing Factor)
Sequence
Signal peptide and human FGF-23 (aa 1-251) are fused at the C-terminus to the Fc portion of human IgG1.
Host
Human, HEK 293 cells
Form/Format
Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.
Purity/Purification
Highly Purified
>90% (SDS-PAGE)
Preparation and Storage
Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Working aliquots are stable for up to 3 months when stored at -20 degree C.
Molecular Weight
~60kD (SDS-PAGE, full-length)
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Activates ERK and FRS2alpha phosphorylation in Klotho expressing cells.

Product Categories/Family for FGF-23:Fc active protein

Growth Factors; Cytokines; Growth Factors-FGF

Other Notes

Small volumes of FGF-23:Fc active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGF-23:Fc purchase

MBS637209 is an active protein targeting FGF-23:Fc. Also known as FGF-23:Fc, Recombinant, Human (Fibroblast Growth Factor 23, Tumor-derived Hypophosphatemia-inducing Factor). Host: Human, HEK 293 cells.
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