C21ORF33 Recombinant Protein – Cat# MBS637238

HES1 (C21ORF33) Recombinant Protein

Name: C21ORF33 Recombinant Protein; HES1; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS637238
Price: 645 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637238

bHLH proteins are essential for neurogenesis, myogenesis, hematopoiesis and sex determination. HES1 (Hairy and Enhancer of Split 1) is a basic Helix-Loop-Helix (bHLH) transcriptional repressor regulated by the Notch pathway and expressed in various tissues.… More details

$645 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HES1 (C21orf33), Recombinant Protein

Full Product Name

HES1, Recombinant, Human (His) (Hairy and Enhancer of Split 1, Transcription Factor HES-1, Class B Basic Helix-loop-helix Protein 39, bHLHb39, Hairy Homolog, Hairy-like Protein, HRY, hHL)

Product Gene Name

C21orf33 recombinant protein

Sequence

Human HES1 (aa 2-280) is fused at the N-terminus to a His-tag.

Host

Human, E Coli

Form/Format

Supplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.

Purity/Purification

Highly Purified
>90% (SDS-PAGE)

Preparation and Storage

Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Working aliquots are stable for up to 3 months when stored at -20 degree C.

Molecular Weight

~35kD (SDS-PAGE)

Chromosome Location

Chromosome: 21; NC_000021.8 (45553476..45622835). Location: 21q22.3

OMIM

601659

3D Structure

ModBase 3D Structure for P30042

Product Categories/Family for C21orf33 recombinant protein

Molecular Biology; MB-Transcription Factors

Other Notes

Small volumes of C21orf33 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C21orf33 purchase

MBS637238 is a recombinant protein targeting C21orf33. Also known as HES1, Recombinant, Human (His) (Hairy and Enhancer of Split 1, Transcription Factor HES-1, Class B Basic Helix-loop-helix Protein 39, bHLHb39, Hairy Homolog, Hairy-like Protein, HRY, hHL). Host: Human, E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for C21orf33. It may not necessarily be applicable to this product.

NCBI GI #

1655594

NCBI GeneID

8209

NCBI Accession #

CAA68857.1

UniProt Primary Accession #

P30042

UniProt Secondary Accession #

O00650; O00660; O15011; O15012; P55346; P78474; Q92505; Q92507; A6NFJ6; A6NJY7

UniProt Related Accession #

P30042

NCBI Official Full Name

HES1

NCBI Official Synonym Full Names

chromosome 21 open reading frame 33

NCBI Official Symbol

C21orf33

NCBI Official Synonym Symbols

ES1; HES1; KNPH; KNPI; GT335

UniProt Protein Name

ES1 protein homolog, mitochondrial

UniProt Synonym Protein Names

Protein GT335; Protein KNP-I

Protein Family

Protein

UniProt Gene Name

C21orf33

UniProt Synonym Gene Names

HES1; KNPI

UniProt Entry Name

ES1_HUMAN

NCBI Protein Information

ES1 protein homolog, mitochondrial; Keio novel protein I; human HES1 protein, homolog to E.coli and zebrafish ES1 protein

NCBI Summary for C21orf33

This gene encodes a potential mitochondrial protein that is a member of the DJ-1/PfpI gene family. This protein is overexpressed in fetal Down syndrome brain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

UniProt Comments for C21orf33

C21orf33: a mitochondrial protein. Two alternatively spliced isoforms have been described.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: mitochondrion

Research Articles on C21orf33

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with C21orf33 recombinant protein

Products by Pathway	Pathway Diagram
Gastric Cancer Network 1 Pathway antibodies	Gastric Cancer Network 1 Pathway Diagram

Diseases associated with C21orf33 recombinant protein

Disease Name	Pubmed Publications
Heart Diseases Antibodies	>1 publications with C21orf33 and Heart Diseases

Organs/Tissues associated with C21orf33 recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>3 publications with C21orf33 and Muscle
Brain Antibodies	>3 publications with C21orf33 and Brain
Heart Antibodies	>2 publications with C21orf33 and Heart
Bone Antibodies	>1 publications with C21orf33 and Bone
Nerve Antibodies	>1 publications with C21orf33 and Nerve
Blood Antibodies	>1 publications with C21orf33 and Blood
Embryonic Tissue Antibodies	>1 publications with C21orf33 and Embryonic Tissue
Bone Marrow Antibodies	>1 publications with C21orf33 and Bone Marrow
Skin Antibodies	>1 publications with C21orf33 and Skin
Placenta Antibodies	>1 publications with C21orf33 and Placenta