VAPA Recombinant Protein – Cat# MBS637377

15% SDS-PAGE (3ug)

VAPA Human (VAPA) Recombinant Protein

Name: VAPA Recombinant Protein; VAPA Human; Human; MyBioSource
Brand: MyBioSource
SKU: MBS637377
Price: 620 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637377

VAPA is a type IV membrane protein, present in the plasma membrane, intracellular vesicles and may also be associated with the cytoskeleton. This protein is a SNARE regulator with high levels of expression in the intestine during late embryogenesis and early… More details

$620 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

VAPA Human, Recombinant Protein

Full Product Name

VAPA, Recombinant Human (hVAP-33, VAP-33, VAP-A, VAP33)

Product Gene Name

VAPA recombinant protein

Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAS ASGAMAKHEQ ILVLDPPTDL KFKGPFTDVV TTNLKLRNPS DRKVCFKVKT TAPRRYCVRP NSGIIDPGST VTVSVMLQPF DYDPNEKSKH KFMVQTIFAP PNTSDMEAVW KEAKPDELMD SKLRCVFEMP NENDKLNDME PSKAVPLNAS KQDGPMPKPH SVSLNDTETR KLMEECKRLQ GEMMKLSEEN RHLRDEGLRL RKVAHSDKPG STSTASFRDN VTSP

Host

E Coli

Form/Format

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 10% glycerol, 1mM DTT.

Purity/Purification

Affinity Purified
~85% by SDS-PAGE.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

29.8kD

Chromosome Location

Chromosome: 18; NC_000018.9 (9913955..9960018). Location: 18p11.22

OMIM

605703

3D Structure

ModBase 3D Structure for Q9P0L0

Endotoxin Level

1EU/1ug (LAL).

Product Categories/Family for VAPA recombinant protein

Molecular Biology; MB-Proteins

Applications Tested/Suitable for VAPA recombinant protein

Western Blot (WB)

Application Notes for VAPA recombinant protein

Suitable for use in Western Blot.

Other Notes

Small volumes of VAPA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VAPA purchase

MBS637377 is a recombinant protein targeting VAPA. Also known as VAPA, Recombinant Human (hVAP-33, VAP-33, VAP-A, VAP33). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for VAPA. It may not necessarily be applicable to this product.

NCBI GI #

94721252

NCBI GeneID

9218

NCBI Accession #

NP_919415.2

UniProt Primary Accession #

Q9P0L0

UniProt Secondary Accession #

O75453; Q5U0E7; Q9UBZ2; A6NDZ0; D3DUI3

UniProt Related Accession #

Q9P0L0

GenBank Nucleotide #

NM_194434.2

NCBI Official Full Name

vesicle-associated membrane protein-associated protein A isoform 2

NCBI Official Synonym Full Names

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

NCBI Official Symbol

VAPA

NCBI Official Synonym Symbols

VAP-A; VAP33; VAP-33; hVAP-33

UniProt Protein Name

Vesicle-associated membrane protein-associated protein A

UniProt Synonym Protein Names

33 kDa VAMP-associated protein

Protein Family

Vesicle-associated membrane protein-associated protein

UniProt Gene Name

VAPA

UniProt Synonym Gene Names

VAP33; VAMP-A; VAMP-associated protein A; VAP-A; VAP-33

UniProt Entry Name

VAPA_HUMAN

NCBI Protein Information

vesicle-associated membrane protein-associated protein A; VAMP-A; VAMP-associated protein A; 33 kDa VAMP-associated protein

NCBI Summary for VAPA

The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

UniProt Comments for VAPA

VAPA: May play a role in vesicle trafficking. Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 18p11.22

Cellular Component: microtubule cytoskeleton; Golgi membrane; endoplasmic reticulum membrane; tight junction; perinuclear region of cytoplasm; endoplasmic reticulum; integral to membrane; plasma membrane; vesicle

Molecular Function: protein domain specific binding; signal transducer activity; protein binding; FFAT motif binding; protein heterodimerization activity; microtubule binding

Biological Process: endoplasmic reticulum organization and biogenesis; cell death; ER to Golgi vesicle-mediated transport; positive regulation of I-kappaB kinase/NF-kappaB cascade; sphingolipid metabolic process; sphingolipid biosynthetic process; signal transduction; neurite development

Research Articles on VAPA

1. Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein VAP-33.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with VAPA recombinant protein

Reference Product	PubMed Publications
VAPB recombinant protein	>33 publications with VAPA and VAPB
OSBP recombinant protein	>9 publications with VAPA and OSBP
COL4A3BP recombinant protein	>6 publications with VAPA and COL4A3BP
NSF recombinant protein	>1 publications with VAPA and NSF
VAMP2 recombinant protein	>1 publications with VAPA and VAMP2
PPM1L recombinant protein	>1 publications with VAPA and PPM1L

Pathways associated with VAPA recombinant protein

Products by Pathway	Pathway Diagram
Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies	Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
Sphingolipid De Novo Biosynthesis Pathway antibodies	Sphingolipid De Novo Biosynthesis Pathway Diagram
Sphingolipid Metabolism Pathway antibodies	Sphingolipid Metabolism Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram

Diseases associated with VAPA recombinant protein

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>33 publications with VAPA and Lung Diseases
Neoplasms Antibodies	>26 publications with VAPA and Neoplasms
Inflammation Antibodies	>7 publications with VAPA and Inflammation
Necrosis Antibodies	>7 publications with VAPA and Necrosis
Weight Loss Antibodies	>3 publications with VAPA and Weight Loss
Cardiovascular Diseases Antibodies	>3 publications with VAPA and Cardiovascular Diseases
Lymphoma Antibodies	>3 publications with VAPA and Lymphoma
Edema Antibodies	>2 publications with VAPA and Edema
Carcinoma, Hepatocellular Antibodies	>1 publications with VAPA and Carcinoma, Hepatocellular
Learning Disorders Antibodies	>1 publications with VAPA and Learning Disorders

Organs/Tissues associated with VAPA recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>49 publications with VAPA and Blood
Brain Antibodies	>21 publications with VAPA and Brain
Lung Antibodies	>20 publications with VAPA and Lung
Liver Antibodies	>14 publications with VAPA and Liver
Nerve Antibodies	>12 publications with VAPA and Nerve
Lymph Antibodies	>9 publications with VAPA and Lymph
Spleen Antibodies	>9 publications with VAPA and Spleen
Lymph Node Antibodies	>9 publications with VAPA and Lymph Node
Bone Antibodies	>8 publications with VAPA and Bone
Bone Marrow Antibodies	>7 publications with VAPA and Bone Marrow