ANXA6 Recombinant Protein – Cat# MBS637427

15% SDS-PAGE using MBS637427 (3ug)

Annexin A6 (ANXA6) Recombinant Protein

Name: ANXA6 Recombinant Protein; Annexin A6; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS637427
Price: 465 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637427

Annexin A6 belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and… More details

$465 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Annexin A6 (Anxa6), Recombinant Protein

Full Product Name

Annexin A6, Recombinant, Human (ANXA6, ANX6, CBP68)

Product Gene Name

Anxa6 recombinant protein

Sequence

MGSSHHHHHH SSGLVPRGSH MAKPAQGAKY RGSIHDFPGF DPNQDAEALY TAMKGFGSDK EAILDIITSR SNRQRQEVCQ SYKSLYGKDL IADLKYELTG KFERLIVGLM RPPAYCDAKE IKDAISGIGT DEKCLIEILA SRTNEQMHQL VAAYKDAYER DLEADIIGDT SGHFQKMLVV LLQGTREEDD VVSEDLVQQD VQDLYEAGEL KWGTDEAQFI YILGNRSKQH LRLVFDEYLK TTGKPIEASI RGELSGDFEK LMLAVVKCIR STPEYFAERL FKAMKGLGTR DNTLIRIMVS RSELDMLDIR EIFRTKYEKS LYSMIKNDTS GEYKKTLLKL SGGDDDAAGQ FFPEAAQVAY QMWELSAVAR VELKGTVRPA NDFNPDADAK ALRKAMKGLG TDEDTIIDII THRSNVQRQQ IRQTFKSHFG RDLMTDLKSE ISGDLARLIL GLMMPPAHYD AKQLKKAMEG AGTDEKALIE ILATRTNAEI RAINEAYKED YHKSLEDALS SDTSGHFRRI LISLATGHRE EGGENLDQAR EDAQVAAEIL EIADTPSGDK TSLETRFMTI LCTRSYPHLR RVFQEFIKMT NYDVEHTIKK EMSGDVRDAF VAIVQSVKNK PLFFADKLYK SMKGAGTDEK TLTRIMVSRS EIDLLNIRRE FIEKYDKSLH QAIEGDTSGD FLKALLALCG GED

Host

E Coli

Form/Format

Supplied as a liquid 20mM Tris-HCl buffer, pH8.0, 10% glycerol, 0.1M NaCl.

Purity/Purification

>90% by SDS-PAGE under reducingconditons and visualized by coomassie blue stain

Concentration

0.5mg/ml (lot specific)

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

78kD

Chromosome Location

Chromosome: 10; NC_005109.3 (40092956..40148290, complement). Location: 10q22

3D Structure

ModBase 3D Structure for P48037

Endotoxin Level

1EU/1ug (LAL).

Product Categories/Family for Anxa6 recombinant protein

Molecular Biology; MB-Annexin

Applications Tested/Suitable for Anxa6 recombinant protein

Western Blot (WB)

Application Notes for Anxa6 recombinant protein

Suitable for use in Western Blot.

Other Notes

Small volumes of Anxa6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Anxa6 purchase

MBS637427 is a recombinant protein targeting Anxa6. Also known as Annexin A6, Recombinant, Human (ANXA6, ANX6, CBP68). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Anxa6. It may not necessarily be applicable to this product.

NCBI GI #

130502086

NCBI GeneID

79125

NCBI Accession #

NP_077070.2

UniProt Primary Accession #

P48037

UniProt Related Accession #

P48037

GenBank Nucleotide #

NM_024156.2

NCBI Official Full Name

annexin A6

NCBI Official Synonym Full Names

annexin A6

NCBI Official Symbol

Anxa6

NCBI Official Synonym Symbols

Anx6; CPB-II

UniProt Protein Name

Annexin A6

UniProt Synonym Protein Names

Annexin VI; Annexin-6; Calcium-binding protein 65/67

Protein Family

Annexin

UniProt Gene Name

Anxa6

UniProt Synonym Gene Names

Anx6; CBP 65/67

UniProt Entry Name

ANXA6_RAT

NCBI Protein Information

annexin A6; CBP 65/67; annexin-6; annexin VI; lipocortin VI; calphobindin-II; chromobindin-20; 67 kDa calelectrin; calcium-binding protein 65/67; calcium-binding protein CATA 65/67

NCBI Summary for Anxa6

Ca(2+)-sensitive phospholipid-binding protein that binds CRHSP-28 [RGD, Feb 2006]

UniProt Comments for Anxa6

ANXA6: a calcium/phospholipid-binding protein that may associate with CD21. May regulate the release of Ca(2+) from intracellular stores. Phosphorylated in response to growth factor stimulation. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.

Protein type: Calcium-binding; Motility/polarity/chemotaxis; Lipid-binding

Cellular Component: protein complex; focal adhesion; membrane; late endosome membrane; lysosomal membrane; perinuclear region of cytoplasm; apical plasma membrane; cytoplasm; melanosome

Molecular Function: protein homodimerization activity; GTP binding; calcium-dependent phospholipid binding; cholesterol binding; calcium ion binding; ligand-gated ion channel activity; lipid binding; calcium-dependent protein binding

Biological Process: secretion; regulation of muscle contraction; calcium ion transport; protein homooligomerization

Research Articles on Anxa6

1. Transient knockdown of annexin A6 in cardiomyocytes by shRNA significantly enhances the contractile functions but does not affect the z-band architecture.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Anxa6 recombinant protein

Products by Pathway	Pathway Diagram
Calcium Regulation In The Cardiac Cell Pathway antibodies	Calcium Regulation In The Cardiac Cell Pathway Diagram
Prostaglandin Synthesis And Regulation Pathway antibodies	Prostaglandin Synthesis And Regulation Pathway Diagram

Organs/Tissues associated with Anxa6 recombinant protein

Organ/Tissue Name	Pubmed Publications
Connective Tissue Antibodies	>4 publications with Anxa6 and Connective Tissue
Muscle Antibodies	>3 publications with Anxa6 and Muscle
Liver Antibodies	>2 publications with Anxa6 and Liver
Nerve Antibodies	>1 publications with Anxa6 and Nerve
Ovary Antibodies	>1 publications with Anxa6 and Ovary
Lung Antibodies	>1 publications with Anxa6 and Lung
Heart Antibodies	>1 publications with Anxa6 and Heart