Rabbit Anti-CYPD Polyclonal Antibody – Cat# MBS6375570

Western Blot analysis of PPID expression in transfected 293T cell line by PPID polyclonal antibody. Lane 1: PPID transfected lysate (40.8kD). Lane 2: Non-transfected lysate.

CYPD Antibody – Rabbit Polyclonal

Name: CYPD Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6375570
Price: 1165 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6375570

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. More details

$1165 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CYPD, Polyclonal Antibody

Full Product Name

CYPD (Cyclophilin-related Protein, Cyclophilin-40, CYP-40, 40kD Peptidyl-prolyl Cis-trans Isomerase, Rotamase D, Peptidyl-prolyl Cis-trans Isomerase D, PPIase D, CYP40, PPID, MGC33096) (FITC)

Product Gene Name

anti-CYPD antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human PPID.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

40,764 Da

OMIM

601753

3D Structure

ModBase 3D Structure for Q08752

Immunogen

Full length human PPID, aa1-370 (NP_005029.1).

Immunogen Sequence

MSHPSPQAKPSNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGHTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGRNTNGSQFFITTVPTPHLDGKHVVFGQVIKGIGVARILENVEVKGEKPAKLCVIAECGELKEGDDGGIFPKDGSGDSHPDFPEDADIDLKDVDKILLITEDLKNIGNTFFKSQNWEMAIKKYAEVLRYVDSSKAVIETADRAKLQPIALSCVLNIGACKLKMSNWQGAIDSCLEALELDPSNTKALYRRAQGWQGLKEYDQALADLKKAQGIAPEDKAIQAELLKVKQKIKAQKDKEKAVYAKMFA

Conjugate

FITC

Note

Preservative Free

Product Categories/Family for anti-CYPD antibody

Antibodies; Cyclophilin

Applications Tested/Suitable for anti-CYPD antibody

Western Blot (WB)

Application Notes for anti-CYPD antibody

Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-CYPD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CYPD purchase

MBS6375570 is an antibody targeting CYPD. Also known as CYPD (Cyclophilin-related Protein, Cyclophilin-40, CYP-40, 40kD Peptidyl-prolyl Cis-trans Isomerase, Rotamase D, Peptidyl-prolyl Cis-trans Isomerase D, PPIase D, CYP40, PPID, MGC33096) (FITC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CYPD. It may not necessarily be applicable to this product.

NCBI GI #

4826932

NCBI GeneID

5481

NCBI Accession #

NP_005029.1

UniProt Primary Accession #

Q08752

UniProt Secondary Accession #

B2R9V2

UniProt Related Accession #

Q08752

GenBank Nucleotide #

NM_005038

NCBI Official Full Name

peptidyl-prolyl cis-trans isomerase D

NCBI Official Synonym Full Names

peptidylprolyl isomerase D

NCBI Official Symbol

PPID

NCBI Official Synonym Symbols

CYPD; CYP-40

UniProt Protein Name

Peptidyl-prolyl cis-trans isomerase D

UniProt Synonym Protein Names

40 kDa peptidyl-prolyl cis-trans isomerase; Cyclophilin-40; CYP-40; Cyclophilin-related protein; Rotamase D

Protein Family

Bifunctional cytochrome P450/NADPH--P450 reductase

UniProt Gene Name

PPID

UniProt Synonym Gene Names

CYP40; CYPD; PPIase D; CYP-40

UniProt Entry Name

PPID_HUMAN

NCBI Protein Information

peptidyl-prolyl cis-trans isomerase D; 40 kDa peptidyl-prolyl cis-trans isomerase D; PPIase D; cyclophilin 40; cyclophilin D; cyclophilin-40; cyclophilin-related protein; rotamase D

NCBI Summary for CYPD

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008]

UniProt Comments for CYPD

PPID: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.

Protein type: Nucleolus; EC 5.2.1.8; Isomerase

Chromosomal Location of Human Ortholog: 4q31.3

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus

Molecular Function: protein binding; peptidyl-prolyl cis-trans isomerase activity; heat shock protein binding; estrogen receptor binding; Hsp90 protein binding; Hsp70 protein binding; cyclosporin A binding; transcription factor binding

Biological Process: release of virus from host; protein transport; protein peptidyl-prolyl isomerization; positive regulation of viral genome replication; positive regulation of protein secretion; protein folding; apoptosis; positive regulation of apoptosis; protein complex assembly; negative regulation of transcription from RNA polymerase II promoter

Research Articles on CYPD

1. The Photorhabdus toxins TccC3 and TccC5 interacted with Hsp90, FKBP51, Cyp40 and CypA, suggesting a role of these host cell factors in translocation and/or refolding of the ADP-ribosyltransferases.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CYPD antibody

Products by Pathway	Pathway Diagram
C-MYB Transcription Factor Network Pathway antibodies	C-MYB Transcription Factor Network Pathway Diagram

Diseases associated with anti-CYPD antibody

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>6 publications with CYPD and Disease Models, Animal
Necrosis Antibodies	>5 publications with CYPD and Necrosis
Hyperplasia Antibodies	>4 publications with CYPD and Hyperplasia
Inflammation Antibodies	>3 publications with CYPD and Inflammation
Hypertrophy Antibodies	>2 publications with CYPD and Hypertrophy
Fibrosis Antibodies	>2 publications with CYPD and Fibrosis
Weight Loss Antibodies	>2 publications with CYPD and Weight Loss
Cardiovascular Diseases Antibodies	>2 publications with CYPD and Cardiovascular Diseases
Hemorrhage Antibodies	>2 publications with CYPD and Hemorrhage
Drug-Induced Liver Injury Antibodies	>2 publications with CYPD and Drug-Induced Liver Injury

Organs/Tissues associated with anti-CYPD antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>38 publications with CYPD and Brain
Blood Antibodies	>36 publications with CYPD and Blood
Heart Antibodies	>3 publications with CYPD and Heart
Liver Antibodies	>3 publications with CYPD and Liver
Lung Antibodies	>2 publications with CYPD and Lung
Prostate Antibodies	>2 publications with CYPD and Prostate
Thyroid Antibodies	>1 publications with CYPD and Thyroid
Pancreas Antibodies	>1 publications with CYPD and Pancreas
Skin Antibodies	>1 publications with CYPD and Skin
Intestine Antibodies	>1 publications with CYPD and Intestine