Elastase, Neutrophil Mouse Active Protein

Neutrophil Elastase (ELA2), also known as polymorphonuclear leukocyte elastase, is a serine protease belonging to the chymotrypsin family. Located primarily in the azurophil granules of polymorphonuclear leukocytes, ELA2 function is the degradation of many extracellular matrix macromolecules. alpha-1 Antitrypsin (Serpin A1) and secretory leukocyte protease inhibitor (SLPI) have been shown to inhibit ELA2 activity. This protein may be involved in lung emphysema, cystic fibrosis, the adult respiratory distress syndrome (ARDS), rheumatoid arthritis, tumor invasion and infectious diseases. The purified recombinant mouse ELA2 does not contain the last five amino acid residues of the deduced amino acid sequence.

Murine myeloma cell line, NSO-derived Ser27-Arg260 with a C-terminallO-His tag.

Small volumes of Elastase, Neutrophil active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS637582 is an active protein targeting Elastase, Neutrophil. Also known as Elastase, Neutrophil, Recombinant, Mouse. Reactive in Mouse.