Leptin, Triple Antagonist Active Protein

Leptin inhibits food intake and stimulates energy expenditure. Leptin also has thermogenic actions and regulates enzymes of fatty acid oxidation. Severe hereditary obesity in rodents and humans is caused by defects in leptin production. In addition to its critical role in the physiologic regulation of body weight leptin has a variety of other physiologic and pathologic functions resembling those of cytokines. These functions include the regulation of hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.

Recombinant human leptin, one polypeptide chain containing 146 amino acids and additional Ala at N-terminus and having a molecular mass of ~16kD, hLEP was mutated, resulting in L39A/D40A/F41A mutant was purified by proprietary chromatographic techniques.

Small volumes of Leptin, Triple Antagonist active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS637633 is an active protein targeting Leptin, Triple Antagonist. Also known as Leptin, Triple Antagonist, Recombinant, Human (Ob, Obese Protein, Obesity Factor). Host: E Coli.