SSX4 Recombinant Protein – Cat# MBS637706

SDS: Analysis of SSX4 Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining.

Synovial Sarcoma, X Breakpoint 4 (SSX4) Recombinant Protein

Name: SSX4 Recombinant Protein; MyBioSource
Brand: MyBioSource
SKU: MBS637706
Price: 690 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637706

This protein belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer… More details

$690 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Synovial Sarcoma, X Breakpoint 4 (SSX4), Recombinant Protein

Full Product Name

Synovial Sarcoma, X Breakpoint 4 (SSX4) Recombinant, Human

Product Gene Name

SSX4 recombinant protein

Host

E Coli

Form/Format

Supplied as a liquid in 10mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% sodium azide, 10mM DTT.

Purity/Purification

Highly Purified
Highly purified

Preparation and Storage

-70 degree C

Molecular Weight

21,858 Da

Chromosome Location

Chromosome: X; NC_000023.10 (48242968..48252785). Location: Xp11.23

OMIM

300326

3D Structure

ModBase 3D Structure for O60224

Species

Homo sapiens

Tag Fusion Partner

T7 Tag

Quality Control

SDS-PAGE Storage and Stability: May be stored at 4 degree C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.

Product Categories/Family for SSX4 recombinant protein

Molecular Biology; MB-Cancer Markers

Applications Tested/Suitable for SSX4 recombinant protein

ELISA (EL/EIA)

Application Notes for SSX4 recombinant protein

Suitable for use in Mass Spectometry, ELISA and Western Blot as an antigen assay standard.

Other Notes

Small volumes of SSX4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SSX4 purchase

MBS637706 is a recombinant protein targeting SSX4. Also known as Synovial Sarcoma, X Breakpoint 4 (SSX4) Recombinant, Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SSX4. It may not necessarily be applicable to this product.

NCBI GI #

13529095

NCBI GeneID

6759

NCBI Accession #

AAH05325.1

UniProt Primary Accession #

O60224

UniProt Secondary Accession #

Q5JQZ0; Q9UJU9; B2RPE3

UniProt Related Accession #

O60224

NCBI Official Full Name

Synovial sarcoma, X breakpoint 4

NCBI Official Synonym Full Names

synovial sarcoma, X breakpoint 4

NCBI Official Symbol

SSX4

NCBI Official Synonym Symbols

CT5.4

UniProt Protein Name

Protein SSX4

UniProt Synonym Protein Names

Cancer/testis antigen 5.4

Protein Family

Protein

UniProt Gene Name

SSX4

UniProt Synonym Gene Names

SSX4A; CT5.4

UniProt Entry Name

SSX4_HUMAN

NCBI Protein Information

protein SSX4; cancer/testis antigen 5.4

NCBI Summary for SSX4

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for SSX4

SSX4: Could act as a modulator of transcription. Belongs to the SSX family.

Protein type: Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: nucleus

Molecular Function: nucleic acid binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent

Research Articles on SSX4

1. we found that the SSX4 and MAGE-A3 genes are frequently expressed in brain tumor cell lines

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SSX4 recombinant protein

Reference Product	PubMed Publications
SS18 recombinant protein	>12 publications with SSX4 and SS18
MAGEA3 recombinant protein	>2 publications with SSX4 and MAGEA3
CTAG2 recombinant protein	>1 publications with SSX4 and CTAG2
SS18L1 recombinant protein	>1 publications with SSX4 and SS18L1
SSX2IP recombinant protein	>1 publications with SSX4 and SSX2IP

Diseases associated with SSX4 recombinant protein

Disease Name	Pubmed Publications
Sarcoma, Synovial Antibodies	>26 publications with SSX4 and Sarcoma, Synovial
Neuroectodermal Tumors Antibodies	>4 publications with SSX4 and Neuroectodermal Tumors
Mycosis Fungoides Antibodies	>1 publications with SSX4 and Mycosis Fungoides
Neoplasms, Neuroepithelial Antibodies	>1 publications with SSX4 and Neoplasms, Neuroepithelial

Organs/Tissues associated with SSX4 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with SSX4 and Blood
Bladder Antibodies	>1 publications with SSX4 and Bladder