Factor Viia Active Protein

Human coagulation factor VII is a single chain protease that circulates in the blood as a weakly active zymogen at concentrations of approximately 10nmol/L. When converted to the active 2 chain form (VIIa), it is a powerful initiator of hemostasis. Recombinant Factor VIIa is a unique hemostatic agent with potential for broad-spectrum applications in bleeding patients with congenital and acquired bleeding abnormalities. At present, recombinant Factor VIIa is only approved for the treatment of hemophilia A and B patients who have acquired antibodies to Factors VIII and IX.

Recombinant Human Factor VIIa produced in BHK is a glycosylated polypeptide two-chain dimer consisting of 406 amino acids with a molecular weight of 50kD.

Small volumes of Factor VIIa active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS637774 is an active protein targeting Factor VIIa. Also known as Factor VIIa, Recombinant, Human. Host: BHK cells.