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CD115, Fc Chimera (CD115) Feline Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637832

CD115 is also known as c-fms, marcophage colony stimulating factor receptor, or CSF-1R. It exists in immature (gp130 c-fms) and mature (gp150 c-fms) forms. CSF-1R exhibits an intrinsic tyrosine-specific protein kinase activity. It is expressed on the cells of… More details

$1125 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD115, Fc Chimera, Active Protein
Full Product Name
CD115, Recombinant, Human, Fc Chimera (BSA Free) (c-fms, Fms, CSF-1R, M-CSFR)
Species Reactivity
Feline
Form/Format
Supplied as a lyophilized powder from a 0.2um sterile-filtered solution in PBS. It is recommended that sterile PBS containing at least 0.1% HSA or BSA be added to the vial to prepare a stock solution of no less than 50mg/ml. Also available with BSA. See C
Purity/Purification
Affinity Purified
97%, as determined by SDS-PAGE and visualized by silver stain.
Preparation and Storage
Lyophilized samples are stable for greater than six months at -20 degree C to -70 degree C. Upon reconstitution, this cytokine can be stored under sterile conditions at 2-4 degree C for one month
or at -20 to -70 degree C for three months without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Activity
Measured by its ability to inhibit the M-CSF induced proliferation of M-NFS-60 cells (Halenbeck, R. et al., 1989, Biotechnology 7:710). The ED50 for this effect is typically 0.004-0.012mg/ml in the presence of 1ng/ml of rhM-CSF.
Endotoxin Level
0.1ng/mg of the cytokine as determined by the LAL method.

Other Notes

Small volumes of CD115, Fc Chimera active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD115, Fc Chimera purchase

MBS637832 is an active protein targeting CD115, Fc Chimera. Also known as CD115, Recombinant, Human, Fc Chimera (BSA Free) (c-fms, Fms, CSF-1R, M-CSFR). Reactive in Feline.
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