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Sigirr:fc (SIGIRR) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637879

SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. More details

$590 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SIGIRR:Fc, Recombinant Protein
Full Product Name
SIGIRR:Fc, Recombinant, Human (Toll/Interleukin-1 Receptor 8, TIR8, Single Ig IL-1R-related Molecule)
Sequence
Signal peptide and extracellu lar domain of human SIGIRR (aa 1-118) are fused at the C-terminus to the Fc portion of human IgG1.
Host
Human, HEK 293 cells
Form/Format
Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.
Purity/Purification
Highly Purified
>90% (SDS-PAGE)
Preparation and Storage
Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Working aliquots are stable for up to 3 months when stored at -20 degree C.
Molecular Weight
~50kD (SDS-PAGE)

Product Categories/Family for SIGIRR:Fc recombinant protein

Molecular Biology; MB-Toll Like Receptors (TLR)

Other Notes

Small volumes of SIGIRR:Fc recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SIGIRR:Fc purchase

MBS637879 is a recombinant protein targeting SIGIRR:Fc. Also known as SIGIRR:Fc, Recombinant, Human (Toll/Interleukin-1 Receptor 8, TIR8, Single Ig IL-1R-related Molecule). Host: Human, HEK 293 cells.
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