GOLGB1 Recombinant Protein – Cat# MBS637983

Structure of the recombinant antibody anti-Giantin (h), mAb (rec.) The single chain variable human fragment (ScFv) selected by antibody phage display technology and specific to the antigen of interest is fused to a human IgG2 Fc region.

Giantin (GOLGB1) Recombinant Protein

Name: GOLGB1 Recombinant Protein; Giantin; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS637983
Price: 725 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637983

Giantin, the largest Golgi membrane protein, is C-terminally anchored to cis- and medial-Golgi membranes and forms a long ~250nm coiled-coil rod that directly interacts with microtubules in a cell-cycle regulated way. It is an excellent marker for mammalian… More details

$725 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Giantin (GOLGB1), Recombinant Protein

Full Product Name

Giantin (Recombinant) (Golgin Subfamily B Member 1, 372 D Golgi Complex-associated Protein, GCP372, Macrogolgin)

Product Gene Name

GOLGB1 recombinant protein

Product Synonym Names

Anti -Giantin (Recombinant) (Golgin Subfamily B Member 1, 372 D Golgi Complex-associated Protein, GCP372, Macrogolgin)

Clonality

Monoclonal

Isotype

IgG2,l

Clone Number

TA10

Host

Human

Form/Format

Supplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.

Purity/Purification

Highly Purified
Purified from HEK 293 cell culture supernatant (>95% (SDS-PAGE).

Specificity

Recognizes human and mouse giantin.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

376,019 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (121382046..121468662, complement). Location: 3q13

OMIM

602500

3D Structure

ModBase 3D Structure for Q14789

Immunogen

Human recombinant giantin.

Product Categories/Family for GOLGB1 recombinant protein

Antibodies; Abs to Golgi Proteins

Applications Tested/Suitable for GOLGB1 recombinant protein

Immunocytochemistry (ICC)

Application Notes for GOLGB1 recombinant protein

Suitable for use in Immunocytochemistry

Other Notes

Small volumes of GOLGB1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GOLGB1 purchase

MBS637983 is a recombinant protein targeting GOLGB1. Also known as Giantin (Recombinant) (Golgin Subfamily B Member 1, 372 D Golgi Complex-associated Protein, GCP372, Macrogolgin). Host: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for GOLGB1. It may not necessarily be applicable to this product.

NCBI GI #

374532823

NCBI GeneID

2804

NCBI Accession #

NP_001243417.1

UniProt Primary Accession #

Q14789

UniProt Secondary Accession #

Q14398; B2ZZ91; D3DN92; E7EP74

UniProt Related Accession #

Q14789

GenBank Nucleotide #

NM_001256488.1

NCBI Official Full Name

Golgin subfamily B member 1 isoform 4

NCBI Official Synonym Full Names

golgin B1

NCBI Official Symbol

GOLGB1

NCBI Official Synonym Symbols

GCP; GCP372; GOLIM1

UniProt Protein Name

Golgin subfamily B member 1

UniProt Synonym Protein Names

372 kDa Golgi complex-associated protein; GCP372; Giantin; Macrogolgin

Protein Family

Golgin subfamily

UniProt Gene Name

GOLGB1

UniProt Synonym Gene Names

GCP372

UniProt Entry Name

GOGB1_HUMAN

NCBI Protein Information

Golgin subfamily B member 1; giantin; macrogolgin; golgi integral membrane protein 1; 372 kDa Golgi complex-associated protein; golgin B1, golgi integral membrane protein; golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1

UniProt Comments for GOLGB1

GOLGB1: May participate in forming intercisternal cross-bridges of the Golgi complex.

Protein type: Membrane protein, integral; Vesicle

Chromosomal Location of Human Ortholog: 3q13

Cellular Component: Golgi membrane; Golgi apparatus; Golgi stack; cis-Golgi network; membrane; ER-Golgi intermediate compartment; integral to membrane

Molecular Function: protein binding

Biological Process: Golgi organization and biogenesis

Research Articles on GOLGB1

1. unbiased whole-genome search for genetic modifiers of stroke risk in sickle cell anemia was performed; mutation in GOLGB1 (Y1212C) and mutation in ENPP1 (K173Q) were confirmed as having significant associations with a decreased risk for stroke

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with GOLGB1 recombinant protein

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>1 publications with GOLGB1 and Brain Diseases
Edema Antibodies	>1 publications with GOLGB1 and Edema
Nervous System Diseases Antibodies	>1 publications with GOLGB1 and Nervous System Diseases

Organs/Tissues associated with GOLGB1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with GOLGB1 and Bone