Lck, P56lck, Active Active Protein

LCK (p56lck) is a member of the Src family of non-receptor tyrosine kinases. It was identified as a gene rearranged and over-expressed in the murine lymphoma LSTRA, most likely as a result of the insertion of Moloney murine leukemia virus DNA immediately adjacent to the gene (1). LCK behaves as a proto-oncogene and can lead to cell transformation upon activation. A number of human cancer cell lines show over-expression of LCK, pointing to a possible role for this kinase in the initiation and maintenance of the transformed state in human cancers (2).

Small volumes of Lck, p56lck, active active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS638203 is an active protein targeting Lck, p56lck, active. Also known as Lck, p56lck, active, Recombinant, Human (Lymphocyte-specific Tyrosine Kinase).