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Il-1r2, Blocking Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS638223

The inflammatory actions of IL-1alpha and beta depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein… More details

$725 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-1R2, blocking, Recombinant Protein
Full Product Name
IL-1R2, blocking (Recombinant) (CD121 Antigen-like Family Member B, IL-1 Type II Receptor, Interleukin-1 Receptor beta, Interleukin-1 Receptor Type II, CD121b)
Product Synonym Names
Anti -IL-1R2, blocking (Recombinant) (CD121 Antigen-like Family Member B, IL-1 Type II Receptor, Interleukin-1 Receptor beta, Interleukin-1 Receptor Type II, CD121b)
Clonality
Monoclonal
Isotype
IgG2b,l
Clone Number
Praxy-1
Host
Mouse
Form/Format
Supplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
Purity/Purification
Highly Purified
>95% (SDS-PAGE)
Specificity
Recognizes mouse IL-1R2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Recombinant mouse IL-1R2 (extracellular domain).

Product Categories/Family for IL-1R2, blocking recombinant protein

Antibodies; Abs to CD Markers
Applications Tested/Suitable for IL-1R2, blocking recombinant protein
ELISA (EL/EIA), Flow Cytometry (FC/FACS)
Application Notes for IL-1R2, blocking recombinant protein
Suitable for use in ELISA, Flow Cytometry, Neutralization

Structure of IL-1R2, blocking recombinant protein

Structure of the recombinant antibody anti-IL-1R2 (mouse), mAb (rec.) The single chain variable human fragment (ScFv) selected by antibody phage display technology and specific to the antigen of interest is fused to a mouse IgG2b Fc region.
Recombinant Protein – Cat# MBS638223

Flow Cytometry (FC/FACS) of IL-1R2, blocking recombinant protein

Detection of endogenous mouse IL-1R2 with IL-1R2 (mouse), mAb (rec.) Method: In vitro-cultivated BMN (mouse Neutrophils) (stimulated 24h with hydrocortisone) were stained with IL-1R2 (mouse), mAb (rec.) (thick green line) or an isotype control (thin black line) at 5μg/ml each, revealed with a secondary anti-mouse antibody (FITC) and then analyzed by flow cytometry.
Recombinant Protein, Flow Cytometry (FC/FACS) – Cat# MBS638223

Other Notes

Small volumes of IL-1R2, blocking recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-1R2, blocking purchase

MBS638223 is a recombinant protein targeting IL-1R2, blocking. Also known as IL-1R2, blocking (Recombinant) (CD121 Antigen-like Family Member B, IL-1 Type II Receptor, Interleukin-1 Receptor beta, Interleukin-1 Receptor Type II, CD121b). Host: Mouse.
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