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Angiostatin Kringles 1-3 Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS638242

Recombinant human Angiostatin is a single, non-glycosylated polypeptide chain containing 259 amino acids and having a molecular mass of ~30kD. rHuAng K1-3 is a proteolytic fragment of plasminogen containing the first three kringle structures. It is more… More details

$540 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Angiostatin Kringles 1-3, Active Protein
Full Product Name
Angiostatin Kringles 1-3, Recombinant, Human
Sequence
VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC DIPRCTTPPP SSGPTYQCLK GTGENYRGNV AVTVSGHTCQ HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGKRAPWCHT TNSQVRWEYC KIPSCDSSP
Host
E Coli
Form/Format
Supplied as a lyophilized powder from 20mM sodium acetate, pH 5.5, 4% mannitol. Reconstitute with sterile ddH20, 0.1% BSA to 0.1-1mg/ml.
Purity/Purification
Highly Purified
>95% as determined by RP-HPLC and SDS-PAGE; Purified by Proprietary chromatographic techniques.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile buffer or ddH2O, 0.1% BSA. Aliquot and store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
~30kD
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Specific Activity
0.55x10e5U/mg based on anti-migration of endothelial cells in vitro.
Biological Activity
Activity is assayed on anti-proliferation and anti-migration of endothelial cells in vitro and anti-angiogenesis in vivo.
Protein Content
Carried out by two independent methods: 1. UV spectroscopy at 280nm using the absorbency value of 2.08 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (Intelligenetics).
2. Analysis by RP-HPLC, using a standard solution of Ang K1-3 as a reference.

Other Notes

Small volumes of Angiostatin Kringles 1-3 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Angiostatin Kringles 1-3 purchase

MBS638242 is an active protein targeting Angiostatin Kringles 1-3. Also known as Angiostatin Kringles 1-3, Recombinant, Human. Host: E Coli.
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