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SGSH Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6394036

SGSH is one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SGSH, Polyclonal Antibody
Full Product Name
SGSH (HSS, N-sulphoglucosamine Sulphohydrolase, Sulfoglucosamine Sulfamidase, Sulphamidase) (AP)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human SGSH.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
56,695 Da
OMIM
252900
3D Structure
ModBase 3D Structure for P51688
Immunogen
Full length human SGSH, aa1-502 (NP_000190.1).
Immunogen Sequence
MSCPVPACCALLLVLGLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNEL
Conjugate
AP
Note
Preservative Free

Product Categories/Family for anti-SGSH antibody

Applications Tested/Suitable for anti-SGSH antibody
Western Blot (WB)
Application Notes for anti-SGSH antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-SGSH antibody

SGSH rabbit polyclonal antibody. Western Blot analysis of SGSH expression in human liver.
Rabbit Anti-SGSH Polyclonal Antibody – Cat# MBS6394036

Western Blot (WB) of anti-SGSH antibody

Western Blot analysis of SGSH expression in transfected 293T cell line by SGSH polyclonal antibody. Lane 1: SGSH transfected lysate (56.7kD). Lane 2: Non-transfected lysate.
Rabbit Anti-SGSH Polyclonal Antibody, Western Blot (WB) – Cat# MBS6394036

Other Notes

Small volumes of anti-SGSH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SGSH purchase

MBS6394036 is an antibody targeting SGSH. Also known as SGSH (HSS, N-sulphoglucosamine Sulphohydrolase, Sulfoglucosamine Sulfamidase, Sulphamidase) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SGSH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
N-sulphoglucosamine sulphohydrolase
NCBI Official Synonym Full Names
N-sulfoglucosamine sulfohydrolase
NCBI Official Symbol
SGSH
NCBI Official Synonym Symbols
HSS; SFMD; MPS3A
UniProt Protein Name
N-sulphoglucosamine sulphohydrolase
UniProt Synonym Protein Names
Sulfoglucosamine sulfamidase; Sulphamidase
UniProt Gene Name
SGSH
UniProt Synonym Gene Names
HSS
UniProt Entry Name
SPHM_HUMAN
NCBI Protein Information
N-sulphoglucosamine sulphohydrolase

NCBI Summary for SGSH

This gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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