Histamine Receptor H4 (HRH4) ELISA Kit for Fish

Name: Fish HRH4 ELISA Kit; Histamine Receptor H4; MyBioSource
Brand: MyBioSource
SKU: MBS063997
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS063997

MBS063997 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Histamine Receptor H4 (HRH4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Product Name

Histamine Receptor H4 (HRH4), ELISA Kit

Full Product Name

Fish Histamine Receptor H4 ELISA Kit

Product Gene Name

HRH4 elisa kit

Species Reactivity

Fish

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

44,496 Da

OMIM

606792

3D Structure

ModBase 3D Structure for Q9H3N8

Other Notes

Small volumes of HRH4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HRH4. It may not necessarily be applicable to this product.

NCBI GI #

219842331

NCBI GeneID

59340

NCBI Accession #

NP_001137300.1

UniProt Primary Accession #

Q9H3N8

UniProt Secondary Accession #

Q4G0I6; Q9GZQ0; B0YJ19; B2KJ48

UniProt Related Accession #

Q9H3N8

GenBank Nucleotide #

NM_001143828.1

NCBI Official Full Name

histamine H4 receptor isoform 2

NCBI Official Synonym Full Names

histamine receptor H4

NCBI Official Symbol

HRH4

NCBI Official Synonym Symbols

H4; H4R; BG26; HH4R; AXOR35; GPRv53; GPCR105

UniProt Protein Name

Histamine H4 receptor

UniProt Synonym Protein Names

AXOR35; G-protein coupled receptor 105; GPRv53; Pfi-013; SP9144

Protein Family

Histamine H4 receptor

UniProt Gene Name

HRH4

UniProt Synonym Gene Names

GPCR105; H4R; HH4R

UniProt Entry Name

HRH4_HUMAN

NCBI Protein Information

histamine H4 receptor; SP9144; pfi-013; G-protein coupled receptor 105

NCBI Summary for HRH4

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

UniProt Comments for HRH4

H4R: The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 18q11.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: histamine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; regulation of MAPKKK cascade; inflammatory response

Research Articles on HRH4

1. Obtained results allow for statement that developed cellular model may be successfully employed in search for new compounds active at histamine H4 receptor

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HRH4 elisa kit

Reference Product	PubMed Publications
HRH3 elisa kit	>7 publications with HRH4 and HRH3
CXCL10 elisa kit	>3 publications with HRH4 and CXCL10
RGS4 elisa kit	>1 publications with HRH4 and RGS4
CCL16 elisa kit	>1 publications with HRH4 and CCL16

Pathways associated with HRH4 elisa kit

Products by Pathway	Pathway Diagram
Amine Ligand-binding Receptors Pathway antibodies	Amine Ligand-binding Receptors Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Other Pathway antibodies	GPCRs, Other Pathway Diagram
Histamine Receptors Pathway antibodies	Histamine Receptors Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram

Diseases associated with HRH4 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>61 publications with HRH4 and Inflammation
Asthma Antibodies	>42 publications with HRH4 and Asthma
Pruritus Antibodies	>28 publications with HRH4 and Pruritus
Neoplasms Antibodies	>21 publications with HRH4 and Neoplasms
Respiratory Hypersensitivity Antibodies	>19 publications with HRH4 and Respiratory Hypersensitivity
Pain Antibodies	>14 publications with HRH4 and Pain
Necrosis Antibodies	>9 publications with HRH4 and Necrosis
Intestinal Diseases Antibodies	>7 publications with HRH4 and Intestinal Diseases
Edema Antibodies	>6 publications with HRH4 and Edema
Hyperalgesia Antibodies	>4 publications with HRH4 and Hyperalgesia

Organs/Tissues associated with HRH4 elisa kit

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>2 publications with HRH4 and Testis