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CRYBB1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641135

MBS641135 is an antibody targeting CRYBB1. Also known as CRYBB1 (Beta-crystallin B1, Beta-B1 Crystallin). Reactive in Human. Host: Mouse. Crystallins are the dominant structural components of the vertebrate eye lens. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CRYBB1, Monoclonal Antibody
Full Product Name
CRYBB1 (Beta-crystallin B1, Beta-B1 Crystallin)
Product Gene Name
Product Synonym Names
Anti -CRYBB1 (Beta-crystallin B1, Beta-B1 Crystallin)
Immunogen Sequence
TTLAPTTVPI TSAKAAELPP GNYRLVVFEL ENFQGRRAEF SGECSNLADR GFDRVRSIIV SAGPWVAFEQ SNFRGEMFIL EKGEYPRWNT WSSSYRSDRL M
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
3D9
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human CRYBB1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
28,023 Da
OMIM
600929
3D Structure
ModBase 3D Structure for P53674
Immunogen
Partial recombinant corresponding to aa37-137 from human CRYBB1 (NP_001878) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-CRYBB1 antibody

Applications Tested/Suitable for anti-CRYBB1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CRYBB1 antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-CRYBB1 antibody

Western Blot detection against Immunogen (36.85kD).
Mouse Anti-CRYBB1 Monoclonal Antibody – Cat# MBS641135

Western Blot (WB) of anti-CRYBB1 antibody

CRYBB1 monoclonal antibody, Western Blot analysis of CRYBB1 expression in MCF-7.
Mouse Anti-CRYBB1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS641135

Testing Data of anti-CRYBB1 antibody

Detection limit for recombinant GST tagged CRYBB1 is ~3ng/ml as a capture antibody.
Mouse Anti-CRYBB1 Monoclonal Antibody, Testing Data – Cat# MBS641135

Other Notes

Small volumes of anti-CRYBB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CRYBB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
CRYBB1
UniProt Protein Name
Beta-crystallin B1
UniProt Synonym Protein Names
Beta-B1 crystallin
Protein Family
UniProt Gene Name
CRYBB1
UniProt Entry Name
CRBB1_HUMAN

UniProt Comments for CRYBB1

CRYBB1: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Specific cleavages in the N-terminal arm occur during lens maturation and give rise to truncated forms, leading to impaired oligomerization and protein insolubilization. The protease responsible for this partial degradation could be calpain II.

Chromosomal Location of Human Ortholog: 22q12.1

Molecular Function: structural constituent of eye lens

Biological Process: visual perception

Disease: Cataract 17, Multiple Types
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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