Sheep Anti-HS6ST3 Polyclonal Antibody – Cat# MBS641187

Heparan Sulfate 6O Sulfotransferase 3/HS6ST3 in Mouse Brain . Heparan Sulfate 6O Sulfotransferase 3/HS6ST3 was detected in perfusion fixed frozen sections of mouse brain (trigeminal ganglion) using Sheep Mouse Heparan Sulfate 6O Sulfotransferase 3/HS6ST3 Antigen Affinity purified Polyclonal Antibody at 5ug/ml overnight at 4 °C. Tissue was stained using the Sheep HRPDAB Cell & Tissue Staining Kit and counterstained with hematoxylin (blue). Specific staining was localized to neuronal cell bodies. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

HS6ST3 Antibody – Sheep Polyclonal

Name: HS6ST3 Antibody; Polyclonal; Sheep; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS641187
Price: 1090 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641187

HS6ST3 (Heparin sulfate 6-O-sulfotransferase 3) is a 60-62kD member of the sulfotransferase 6 family of enzymes. It is one of three 6-O sulfotransferase isoforms, all of which essentially perform the same function, but all of which are the products of… More details

$1090 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HS6ST3, Polyclonal Antibody

Full Product Name

HS6ST3 (Heparan sulfate 6-O-sulfotransferase 3)

Product Gene Name

anti-HS6ST3 antibody

Product Synonym Names

Anti -HS6ST3 (Heparan sulfate 6-O-sulfotransferase 3)

Clonality

Polyclonal

Isotype

IgG

Host

Sheep

Species Reactivity

Mouse

Form/Format

Supplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 200ug/ml.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes mouse HS6ST3.

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

54,844 Da

Chromosome Location

Chromosome: 13; NC_000013.10 (96743093..97491816). Location: 13q32.1

OMIM

609401

3D Structure

ModBase 3D Structure for Q8IZP7

Immunogen

Recombinant corresponding to aa28-470 from mouse HS6ST3 expressed in CHO cells (NP_056635).

Product Categories/Family for anti-HS6ST3 antibody

Antibodies; Abs to Enzymes; Sulfotransferase

Applications Tested/Suitable for anti-HS6ST3 antibody

Immunohistochemistry (IHC)

Application Notes for anti-HS6ST3 antibody

Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry: 5-15ug/ml

Other Notes

Small volumes of anti-HS6ST3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HS6ST3 purchase

MBS641187 is an antibody targeting HS6ST3. Also known as HS6ST3 (Heparan sulfate 6-O-sulfotransferase 3). Reactive in Mouse. Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for HS6ST3. It may not necessarily be applicable to this product.

NCBI GI #

45580707

NCBI GeneID

266722

NCBI Accession #

NP_703157.2

UniProt Primary Accession #

Q8IZP7

UniProt Secondary Accession #

Q5W0L0; Q68CW6

UniProt Related Accession #

Q8IZP7

GenBank Nucleotide #

NM_153456.3

NCBI Official Full Name

heparan-sulfate 6-O-sulfotransferase 3

NCBI Official Synonym Full Names

heparan sulfate 6-O-sulfotransferase 3

NCBI Official Symbol

HS6ST3

NCBI Official Synonym Symbols

HS6ST-3

UniProt Protein Name

Heparan-sulfate 6-O-sulfotransferase 3

Protein Family

Heparan-sulfate 6-O-sulfotransferase

UniProt Gene Name

HS6ST3

UniProt Synonym Gene Names

HS6ST-3

UniProt Entry Name

H6ST3_HUMAN

NCBI Protein Information

heparan-sulfate 6-O-sulfotransferase 3

NCBI Summary for HS6ST3

Heparan sulfate (HS) sulfotransferases, such as HS6ST3, modify HS to generate structures required for interactions between HS and a variety of proteins. These interactions are implicated in proliferation and differentiation, adhesion, migration, inflammation, blood coagulation, and other diverse processes (Habuchi et al., 2000 [PubMed 10644753]).[supplied by OMIM, Mar 2008]

UniProt Comments for HS6ST3

HS6ST3: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Belongs to the sulfotransferase 6 family.

Protein type: Glycan Metabolism - heparan sulfate biosynthesis; Transferase; EC 2.8.2.-; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q32.1

Cellular Component: integral to membrane

Molecular Function: heparan sulfate 6-O-sulfotransferase activity

Biological Process: heparan sulfate proteoglycan biosynthetic process, enzymatic modification

Research Articles on HS6ST3

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HS6ST3 antibody

Reference Product	PubMed Publications
NDST3 antibody	>1 publications with HS6ST3 and NDST3

Pathways associated with anti-HS6ST3 antibody

Products by Pathway	Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway antibodies	Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway Diagram
Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway antibodies	Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
HS-GAG Biosynthesis Pathway antibodies	HS-GAG Biosynthesis Pathway Diagram
Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway antibodies	Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway Diagram
MPS I - Hurler Syndrome Pathway antibodies	MPS I - Hurler Syndrome Pathway Diagram
MPS II - Hunter Syndrome Pathway antibodies	MPS II - Hunter Syndrome Pathway Diagram
MPS IIIA - Sanfilippo Syndrome A Pathway antibodies	MPS IIIA - Sanfilippo Syndrome A Pathway Diagram
MPS IIIB - Sanfilippo Syndrome B Pathway antibodies	MPS IIIB - Sanfilippo Syndrome B Pathway Diagram

Diseases associated with anti-HS6ST3 antibody

Disease Name	Pubmed Publications
Maxillofacial Abnormalities Antibodies	>1 publications with HS6ST3 and Maxillofacial Abnormalities
Cleft Palate Antibodies	>1 publications with HS6ST3 and Cleft Palate
Cleft Lip Antibodies	>1 publications with HS6ST3 and Cleft Lip
Congenital Abnormalities Antibodies	>1 publications with HS6ST3 and Congenital Abnormalities
Neoplasms Antibodies	>1 publications with HS6ST3 and Neoplasms

Organs/Tissues associated with anti-HS6ST3 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with HS6ST3 and Brain
Lung Antibodies	>2 publications with HS6ST3 and Lung
Eye Antibodies	>2 publications with HS6ST3 and Eye
Embryonic Tissue Antibodies	>1 publications with HS6ST3 and Embryonic Tissue
Kidney Antibodies	>1 publications with HS6ST3 and Kidney