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MCOLN3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641267

Mucolipins constitute a family of cation channel proteins with homologs in mouse, Drosophila, and C. elegans. Mutations in the human MCOLN1 gene (MIM 605248) cause mucolipodosis IV (MIM 262650). More details

$895 / 0.2 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MCOLN3, Polyclonal Antibody
Full Product Name
MCOLN3, CT (MCOLN3, Mucolipin-3)
Product Gene Name
Product Synonym Names
Anti -MCOLN3, CT (MCOLN3, Mucolipin-3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
64,248 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (85483765..85514585, complement). Location: 1p22.3
OMIM
607400
3D Structure
ModBase 3D Structure for Q8TDD5
Immunogen
MCOLN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-546 amino acids from the C-terminal region of human MCOLN3.

Product Categories/Family for anti-MCOLN3 antibody

Applications Tested/Suitable for anti-MCOLN3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-MCOLN3 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-MCOLN3 antibody

MCOLN3 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MCOLN3 antibody detected the MCOLN3 protein (arrow).
Rabbit Anti-MCOLN3 Polyclonal Antibody – Cat# MBS641267

Other Notes

Small volumes of anti-MCOLN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MCOLN3 purchase

MBS641267 is an antibody targeting MCOLN3. Also known as MCOLN3, CT (MCOLN3, Mucolipin-3). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MCOLN3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mucolipin-3 isoform 2
NCBI Official Synonym Full Names
mucolipin 3
NCBI Official Symbol
MCOLN3
NCBI Official Synonym Symbols
TRPML3; TRP-ML3
UniProt Protein Name
Mucolipin-3
Protein Family
UniProt Gene Name
MCOLN3
UniProt Entry Name
MCLN3_HUMAN
NCBI Protein Information
mucolipin-3

NCBI Summary for MCOLN3

This gene encodes one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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UniProt Comments for MCOLN3

MCOLN3: one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Channel, cation

Chromosomal Location of Human Ortholog: 1p22.3

Cellular Component: cytoplasm; integral to membrane; plasma membrane

Biological Process: locomotory behavior; auditory receptor cell differentiation; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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