Rabbit Anti-SLC39A6 Polyclonal Antibody – Cat# MBS641268

SLC39A6 Antibody western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SLC39A6 antibody detected the SLC39A6 protein (arrow).

SLC39A6 Antibody – Rabbit Polyclonal

Name: SLC39A6 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS641268
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641268

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SLC39A6, Polyclonal Antibody

Full Product Name

SLC39A6, ID (SLC39A6, LIV1, ZIP6, Zinc transporter ZIP6, Estrogen-regulated protein LIV-1, Solute carrier family 39 member 6, Zrt- and Irt-like protein 6)

Product Gene Name

anti-SLC39A6 antibody

Product Synonym Names

Anti -SLC39A6, ID (SLC39A6, LIV1, ZIP6, Zinc transporter ZIP6, Estrogen-regulated protein LIV-1, Solute carrier family 39 member 6, Zrt- and Irt-like protein 6)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recongnizes human SLC39A6

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Chromosome Location

Chromosome: 18; NC_000018.9 (33688494..33709357, complement). Location: 18q12.2

OMIM

608731

3D Structure

ModBase 3D Structure for Q13433

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 437-466 in the central region of human SLC39A6

Product Categories/Family for anti-SLC39A6 antibody

Antibodies; Abs to Transport Proteins

Applications Tested/Suitable for anti-SLC39A6 antibody

ELISA (EL/EIA), Western Blot (WB)

Other Notes

Small volumes of anti-SLC39A6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC39A6 purchase

MBS641268 is an antibody targeting SLC39A6. Also known as SLC39A6, ID (SLC39A6, LIV1, ZIP6, Zinc transporter ZIP6, Estrogen-regulated protein LIV-1, Solute carrier family 39 member 6, Zrt- and Irt-like protein 6). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC39A6. It may not necessarily be applicable to this product.

NCBI GI #

34782898

NCBI GeneID

25800

NCBI Accession #

AAH08317.2

UniProt Primary Accession #

Q13433

UniProt Secondary Accession #

Q8IXR3; Q96HP5; B4DR49; B4E224

UniProt Related Accession #

Q13433

NCBI Official Full Name

SLC39A6 protein, partial

NCBI Official Synonym Full Names

solute carrier family 39 (zinc transporter), member 6

NCBI Official Symbol

SLC39A6

NCBI Official Synonym Symbols

LIV-1

UniProt Protein Name

Zinc transporter ZIP6

UniProt Synonym Protein Names

Estrogen-regulated protein LIV-1; Solute carrier family 39 member 6; Zrt- and Irt-like protein 6

Protein Family

Zinc transporter

UniProt Gene Name

SLC39A6

UniProt Synonym Gene Names

LIV1; ZIP6; ZIP-6

UniProt Entry Name

S39A6_HUMAN

NCBI Protein Information

zinc transporter ZIP6; ZIP-6; zrt- and Irt-like protein 6; estrogen-regulated protein LIV-1; LIV-1 protein, estrogen regulated; solute carrier family 39 member 6; solute carrier family 39 (metal ion transporter), member 6

UniProt Comments for SLC39A6

SLC39A6: May act as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter, SLC family; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 18q12.2

Cellular Component: cell surface; endoplasmic reticulum; integral to plasma membrane; plasma membrane

Molecular Function: zinc ion transmembrane transporter activity

Biological Process: cellular zinc ion homeostasis; transmembrane transport

Research Articles on SLC39A6

1. Down-regulated LIV-1 cells showed significant inhibition of proliferation in vitro and reduction of tumor growth in vivo. Furthermore, E-cadherin expression increased in LIV-1 siRNA expressing Hep-G2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SLC39A6 antibody

Products by Pathway	Pathway Diagram
Metal Ion SLC Transporters Pathway antibodies	Metal Ion SLC Transporters Pathway Diagram
SLC-mediated Transmembrane Transport Pathway antibodies	SLC-mediated Transmembrane Transport Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram
Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies	Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram
Zinc Influx Into Cells By The SLC39 Gene Family Pathway antibodies	Zinc Influx Into Cells By The SLC39 Gene Family Pathway Diagram
Zinc Transporters Pathway antibodies	Zinc Transporters Pathway Diagram

Diseases associated with anti-SLC39A6 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>22 publications with SLC39A6 and Neoplasms
Breast Neoplasms Antibodies	>13 publications with SLC39A6 and Breast Neoplasms
Neoplasm Metastasis Antibodies	>9 publications with SLC39A6 and Neoplasm Metastasis
Death Antibodies	>4 publications with SLC39A6 and Death
Brain Diseases Antibodies	>3 publications with SLC39A6 and Brain Diseases
Carcinoma, Squamous Cell Antibodies	>3 publications with SLC39A6 and Carcinoma, Squamous Cell
Esophageal Squamous Cell Carcinoma Antibodies	>2 publications with SLC39A6 and Esophageal Squamous Cell Carcinoma
Nervous System Diseases Antibodies	>2 publications with SLC39A6 and Nervous System Diseases
Immune System Diseases Antibodies	>2 publications with SLC39A6 and Immune System Diseases
Infertility, Male Antibodies	>1 publications with SLC39A6 and Infertility, Male

Organs/Tissues associated with anti-SLC39A6 antibody

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>5 publications with SLC39A6 and Embryonic Tissue
Lymph Antibodies	>5 publications with SLC39A6 and Lymph
Brain Antibodies	>5 publications with SLC39A6 and Brain
Liver Antibodies	>2 publications with SLC39A6 and Liver
Ovary Antibodies	>2 publications with SLC39A6 and Ovary
Testis Antibodies	>2 publications with SLC39A6 and Testis
Blood Antibodies	>2 publications with SLC39A6 and Blood
Intestine Antibodies	>1 publications with SLC39A6 and Intestine
Pancreas Antibodies	>1 publications with SLC39A6 and Pancreas
Mouth Antibodies	>1 publications with SLC39A6 and Mouth